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CG14221 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32961, updated on 9-Dec-2024

Summary

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Official Symbol
CG14221provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031042
Locus tag
Dmel_CG14221
See related
AllianceGenome:FB:FBgn0031042
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG14221
Summary
Is expressed in spermatozoon. Orthologous to human NME9 (NME/NM23 family member 9). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG14221 in Genome Data Viewer
Location:
18D7-18D7; 1-63 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19618819..19621245, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19512852..19515278, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene tyler Neighboring gene shawn Neighboring gene uncharacterized protein Neighboring gene Translocase of inner membrane 9b Neighboring gene Phosphoseryl tRNA kinase Neighboring gene N(alpha)-acetyltransferase 20 A Neighboring gene MAPK Phosphatase 4 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
  2. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
  3. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
  4. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848
  5. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
uncharacterized protein
Names
CG14221-PB
CG14221-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    19618819..19621245 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272784.1 → NP_001259713.1  uncharacterized protein Dmel_CG14221, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259713.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PHK6
    Conserved Domains (2) summary
    pfam15928
    Location:233 → 508
    DUF4746; Domain of unknown function (DUF4746)
    cl00388
    Location:11 → 111
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  2. NM_134486.3 → NP_608330.2  uncharacterized protein Dmel_CG14221, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608330.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V4X7, Q9VWF6
    Conserved Domains (2) summary
    pfam15928
    Location:189 → 464
    DUF4746; Domain of unknown function (DUF4746)
    cl00388
    Location:1 → 67
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PHK6 M9PHK6
Q9VWF6 Q9VWF6

Gene LinkOut

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