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CG32532 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32943, updated on 9-Dec-2024

Summary

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Official Symbol
CG32532provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0052532
Locus tag
Dmel_CG32532
See related
AllianceGenome:FB:FBgn0052532
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14201; CG14202; CG14203; Dmel\CG32532
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in organism. Human ortholog(s) of this gene implicated in hypogonadism; hypopituitarism; and panhypopituitarism. Orthologous to several human genes including ESX1 (ESX homeobox 1); PROP1 (PROP paired-like homeobox 1); and RHOXF1 (Rhox homeobox family member 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG32532 in Genome Data Viewer
Location:
18C8-18C8; 1-62 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19531851..19547482, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19425884..19441515, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene CoRest Neighboring gene uncharacterized protein Neighboring gene mir-9369 stem loop Neighboring gene mir-972 stem loop

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. X-linked small GTPase and OXPHOS genes are candidates for the genetic basis of hybrid inviability in Drosophila. Hutter P. Dev Genes Evol, 2002 Nov. PMID 12424521
  2. Pax3/7 genes reveal conservation and divergence in the arthropod segmentation hierarchy. Davis GK, et al. Dev Biol, 2005 Sep 1. PMID 16083872
  3. The fly CAMTA transcription factor potentiates deactivation of rhodopsin, a G protein-coupled light receptor. Han J, et al. Cell, 2006 Nov 17. PMID 17110341
  4. Evolution of homeobox genes: Q50 Paired-like genes founded the Paired class. Galliot B, et al. Dev Genes Evol, 1999 Mar. PMID 10079362
  5. Female Genetic Contributions to Sperm Competition in Drosophila melanogaster. Chen DS, et al. Genetics, 2019 Jul. PMID 31101677, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG32532-PB
CG32532-PC
CG32532-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    19531851..19547482 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298513.1 → NP_001285442.1  uncharacterized protein Dmel_CG32532, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285442.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B9EQW3, X2JL88
    Conserved Domains (1) summary
    pfam00046
    Location:183 → 237
    Homeobox; Homeobox domain

  2. NM_134474.5 → NP_608318.5  uncharacterized protein Dmel_CG32532, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608318.5

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VWH1
    Conserved Domains (1) summary
    pfam00046
    Location:513 → 566
    Homeobox; Homeobox domain

  3. NM_001298514.1 → NP_001285443.1  uncharacterized protein Dmel_CG32532, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285443.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B9EQW3, X2JFS5
    Conserved Domains (1) summary
    pfam00046
    Location:183 → 236
    Homeobox; Homeobox domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VWH1 Q9VWH1
X2JFS5 X2JFS5
X2JL88 X2JL88

Gene LinkOut

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