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Kcnrg potassium channel regulator [ Mus musculus (house mouse) ]

Gene ID: 328424, updated on 27-Nov-2024

Summary

Official Symbol
Kcnrgprovided by MGI
Official Full Name
potassium channel regulatorprovided by MGI
Primary source
MGI:MGI:2685591
See related
Ensembl:ENSMUSG00000046168 AllianceGenome:MGI:2685591
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Clld4; Gm745; E030012H22Rik
Summary
Predicted to enable identical protein binding activity. Predicted to be involved in negative regulation of delayed rectifier potassium channel activity. Predicted to be active in endoplasmic reticulum. Orthologous to human KCNRG (potassium channel regulator). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in lung adult (RPKM 1.7), limb E14.5 (RPKM 1.3) and 23 other tissues See more
Orthologs
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Genomic context

See Kcnrg in Genome Data Viewer
Location:
14 D1; 14 33.16 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (61844905..61850282)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (61607457..61612833)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene SPRY domain containing 7 Neighboring gene vomeronasal 1 receptor, pseudogene 136 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:62175814-62175923 Neighboring gene proteasome (prosome, macropain) subunit, alpha type 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_36882 Neighboring gene STARR-seq mESC enhancer starr_36883 Neighboring gene tripartite motif-containing 13 Neighboring gene deleted in lymphocytic leukemia, 2 Neighboring gene microRNA 16-1 Neighboring gene microRNA 15a

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
potassium channel regulatory protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039105.4NP_001034194.1  potassium channel regulatory protein isoform 1

    See identical proteins and their annotated locations for NP_001034194.1

    Status: VALIDATED

    Source sequence(s)
    AC154660
    Consensus CDS
    CCDS27187.1
    UniProtKB/Swiss-Prot
    B2RV87, B7ZWD9, Q2TUM3, Q6P8J6, Q8C6V1
    Related
    ENSMUSP00000055327.9, ENSMUST00000051184.10
    Conserved Domains (2) summary
    smart00225
    Location:7106
    BTB; Broad-Complex, Tramtrack and Bric a brac
    cl02518
    Location:794
    BTB; BTB/POZ domain
  2. NM_206974.2NP_996857.1  potassium channel regulatory protein isoform 2

    See identical proteins and their annotated locations for NP_996857.1

    Status: VALIDATED

    Source sequence(s)
    AC154660
    Consensus CDS
    CCDS88684.1
    UniProtKB/Swiss-Prot
    Q2TUM3
    Related
    ENSMUSP00000153429.2, ENSMUST00000225582.2
    Conserved Domains (2) summary
    smart00225
    Location:7106
    BTB; Broad-Complex, Tramtrack and Bric a brac
    cl02518
    Location:794
    BTB; BTB/POZ domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    61844905..61850282
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)