U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Swt1 Swt1 RNA endoribonuclease [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32788, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Swt1provided by FlyBase
Official Full Name
Swt1 RNA endoribonucleaseprovided by FlyBase
Primary source
FLYBASE:FBgn0030892
Locus tag
Dmel_CG7206
See related
AllianceGenome:FB:FBgn0030892
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7206; Dmel\CG7206; DmSwt1
Summary
Predicted to enable RNA endonuclease activity. Predicted to be involved in nuclear mRNA surveillance of mRNP export. Is expressed in organism. Orthologous to human SWT1 (SWT1 RNA endoribonuclease homolog). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Swt1 in Genome Data Viewer
Location:
16F6-16F6; 1-59 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (18088725..18090509, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17982758..17984542, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Dynein heavy chain at 16F Neighboring gene uncharacterized protein Neighboring gene transcriptional Adaptor 3 Neighboring gene Rho GTPase activating protein at 16F Neighboring gene scully

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes. Skruzný M, et al. PLoS Biol, 2009 Jan 6. PMID 19127978, Free PMC Article
  2. Differential gene expression related to Nora virus infection of Drosophila melanogaster. Cordes EJ, et al. Virus Res, 2013 Aug. PMID 23603562, Free PMC Article
  3. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article
  4. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article
  5. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA endonuclease activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear mRNA surveillance of mRNP export ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Swt1 RNA endoribonuclease
Names
CG7206-PB
CG7206-PC
Swt1-PB
Swt1-PC

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    18088725..18090509 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206776.2 → NP_996499.1  Swt1 RNA endoribonuclease, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996499.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F3YDM7, Q7KUW4
    Conserved Domains (1) summary
    cd09880
    Location:254 → 392
    PIN_Smg5-Smg6-like; PIN domain

  2. NM_001258799.1 → NP_001245728.1  Swt1 RNA endoribonuclease, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245728.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NFB4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9NFB4 M9NFB4
Q7KUW4 Q7KUW4
Q9VWY9 Q9VWY9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools