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CG15373 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32784, updated on 9-Dec-2024

Summary

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Official Symbol
CG15373provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030889
Locus tag
Dmel_CG15373
See related
AllianceGenome:FB:FBgn0030889
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG15373
Summary
Predicted to enable beta-tubulin binding activity and microtubule binding activity. Is expressed in spermatogonium. Orthologous to human DNAI7 (dynein axonemal intermediate chain 7). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG15373 in Genome Data Viewer
Location:
16F5-16F5; 1-59 cM
Exon count:
13
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (18043991..18048720)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17938104..17942753)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Shaker Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Dynein heavy chain at 16F Neighboring gene uncharacterized protein Neighboring gene transcriptional Adaptor 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
  2. A comparative genomic analysis of two distant diptera, the fruit fly, Drosophila melanogaster, and the malaria mosquito, Anopheles gambiae. Bolshakov VN, et al. Genome Res, 2002 Jan. PMID 11779831, Free PMC Article
  3. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
  4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
  5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables beta-tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG15373-PD
CG15373-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    18043991..18048720
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001103543.3 → NP_001097013.2  uncharacterized protein Dmel_CG15373, isoform E [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8JUM9
    Conserved Domains (2) summary
    pfam12366
    Location:908 → 1118
    Casc1; Cancer susceptibility candidate 1
    pfam15927
    Location:14 → 267
    Casc1_N; Cancer susceptibility candidate 1 N-terminus

  2. NM_133036.3 → NP_573264.2  uncharacterized protein Dmel_CG15373, isoform D [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VWZ4
    Conserved Domains (2) summary
    pfam12366
    Location:879 → 1089
    Casc1; Cancer susceptibility candidate 1
    pfam15927
    Location:14 → 234
    Casc1_N; Cancer susceptibility candidate 1 N-terminus
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8JUM9 A8JUM9
Q9VWZ4 Q9VWZ4

Gene LinkOut

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