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RAC2 Rac family small GTPase 2 [ Bos taurus (domestic cattle) ]

Gene ID: 327671, updated on 30-Jan-2025

Summary

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Official Symbol
RAC2provided by VGNC
Official Full Name
Rac family small GTPase 2provided by VGNC
Primary source
VGNC:VGNC:49061
See related
BGD:BT25290; EnsemblRapid:ENSBTAG00070017801
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See RAC2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (75656456..75673385, complement)

Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene interleukin-2 receptor subunit beta Neighboring gene C1q and TNF related 6 Neighboring gene somatostatin receptor 3 Neighboring gene microRNA mir-1835 Neighboring gene cytohesin 4 Neighboring gene extracellular leucine rich repeat and fibronectin type III domain containing 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Cloning and characterization of bovine low molecular weight GTPases (Rac1 and Rac2) and rho GDP-dissociation inhibitor 2 (D4-GDI). Davis AR, et al. Vet Immunol Immunopathol, 2000 May 23. PMID 10802295
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cortical cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in engulfment of apoptotic cell IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment or maintenance of cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in motor neuron axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras-related C3 botulinum toxin substrate 2
Names
p21-Rac2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175792.2 → NP_786986.1  ras-related C3 botulinum toxin substrate 2

    See identical proteins and their annotated locations for NP_786986.1

    Status: VALIDATED

    Source sequence(s)
    AF175263
    UniProtKB/Swiss-Prot
    Q3T0U8, Q9TU25
    UniProtKB/TrEMBL
    A0A3Q1M2K9, B0JYN9
    Related
    ENSBTAP00070023704.1, ENSBTAT00070040147.1
    Conserved Domains (1) summary
    cd01871
    Location:3 → 176
    Rac1_like; Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)-like consists of Rac1, Rac2 and Rac3

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    75656456..75673385 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024991399.2 → XP_024847167.1  ras-related C3 botulinum toxin substrate 2 isoform X1

    Conserved Domains (1) summary
    cl21455
    Location:3 → 150
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9TU25.1 GenPept UniProtKB/Swiss-Prot:Q9TU25

Gene LinkOut

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