ppp2r2ab protein phosphatase 2, regulatory subunit B, alpha b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ppp2r2abprovided by ZNC
Official Full Name: protein phosphatase 2, regulatory subunit B, alpha bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5474
See related: Ensembl:ENSDARG00000006624 AllianceGenome:ZFIN:ZDB-GENE-030131-5474
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: MDS026; ppp2r2a; ppp2r2d; zgc:63780; wu:fd19g04
Summary: Predicted to enable protein phosphatase regulator activity. Acts upstream of or within blood vessel lumenization. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol. Orthologous to human PPP2R2A (protein phosphatase 2 regulatory subunit Balpha). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 10

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (18877353..18907239)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (18919919..18949805)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein phosphatase regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein phosphatase regulator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within blood vessel lumenization	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
part_of protein phosphatase type 2A complex	IBA Inferred from Biological aspect of Ancestor more info
part_of protein phosphatase type 2A complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

NP_001296367.1

EC 3.1.3.16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001309438.1 → NP_001296367.1 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

Status: VALIDATED

Source sequence(s)

AL928714, BX324160

UniProtKB/TrEMBL

A0A8M1P1K5, A2BG80, F6NV52, Q6PGU9

Related

ENSDARP00000117378.1, ENSDART00000138334.3

Conserved Domains (2) summary

COG5170
Location:8 → 443

CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]

sd00039
Location:32 → 80

7WD40; WD40 repeat [structural motif]