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CG5004 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32698, updated on 4-Jan-2025

Summary

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Official Symbol
CG5004provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0260748
Locus tag
Dmel_CG5004
See related
AllianceGenome:FB:FBgn0260748
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-15Db; Dmel\CG5004
Summary
Human ortholog(s) of this gene implicated in osteogenesis imperfecta. Orthologous to several human genes including PHLDB1 (pleckstrin homology like domain family B member 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG5004 in Genome Data Viewer
Location:
15E3-15E5; 1-57 cM
Exon count:
15
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (17107582..17135988)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17001615..17030021)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Actin-related protein 2/3 complex, subunit 3B Neighboring gene ncRNA Neighboring gene meiotic 218 Neighboring gene meiotic 217 Neighboring gene Ribosomal protein S5a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-guided transcript assembly by integrative analysis of RNA sequence data. Boley N, et al. Nat Biotechnol, 2014 Apr. PMID 24633242, Free PMC Article
  2. Single-Step Affinity Purification of ERK Signaling Complexes Using the Streptavidin-Binding Peptide (SBP) Tag. Yang L, et al. Methods Mol Biol, 2017. PMID 27924562, Free PMC Article
  3. Introgression in the Drosophila subobscura--D. Madeirensis sister species: evidence of gene flow in nuclear genes despite mitochondrial differentiation. Herrig DK, et al. Evolution, 2014 Mar. PMID 24152112, Free PMC Article
  4. Cloning of the Drosophila melanogaster meiotic recombination gene mei-218: a genetic and molecular analysis of interval 15E. McKim KS, et al. Genetics, 1996 Sep. PMID 8878687, Free PMC Article
  5. Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge. Fukuyama H, et al. Proc Natl Acad Sci U S A, 2013 Jun 25. PMID 23749869, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

General protein information

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Preferred Names
uncharacterized protein
Names
CG5004-PA
CG5004-PB
CG5004-PC
CG5004-PD
CG5004-PE
CG5004-PF
anon-15Db
transcript b

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    17107582..17135988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132967.3 → NP_573195.1  uncharacterized protein Dmel_CG5004, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573195.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VX80
    Related
    FBpp0074160
    Conserved Domains (3) summary
    pfam00169
    Location:1143 → 1237
    PH; PH domain
    pfam00498
    Location:41 → 104
    FHA; FHA domain
    cl17171
    Location:1142 → 1242
    PH-like; Pleckstrin homology-like domain

  2. NM_001201726.1 → NP_001188655.1  uncharacterized protein Dmel_CG5004, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188655.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9MSQ1
    Conserved Domains (2) summary
    pfam00169
    Location:1043 → 1137
    PH; PH domain
    cl17171
    Location:1042 → 1142
    PH-like; Pleckstrin homology-like domain

  3. NM_001201725.2 → NP_001188654.1  uncharacterized protein Dmel_CG5004, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188654.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9MSQ1
    Conserved Domains (2) summary
    pfam00169
    Location:1043 → 1137
    PH; PH domain
    cl17171
    Location:1042 → 1142
    PH-like; Pleckstrin homology-like domain

  4. NM_001316634.1 → NP_001303563.1  uncharacterized protein Dmel_CG5004, isoform F [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0S0X119
    Conserved Domains (2) summary
    pfam00169
    Location:117 → 211
    PH; PH domain
    cl17171
    Location:116 → 216
    PH-like; Pleckstrin homology-like domain

  5. NM_001201727.1 → NP_001188656.1  uncharacterized protein Dmel_CG5004, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188656.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F3YDC5, M9MSF4
    Conserved Domains (2) summary
    pfam00169
    Location:224 → 318
    PH; PH domain
    cl17171
    Location:223 → 323
    PH-like; Pleckstrin homology-like domain

  6. NM_001298430.1 → NP_001285359.1  uncharacterized protein Dmel_CG5004, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285359.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2JFU3
    Conserved Domains (2) summary
    pfam00169
    Location:173 → 267
    PH; PH domain
    cl17171
    Location:172 → 272
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0S0X119 A0A0S0X119
M9MSF4 M9MSF4
M9MSQ1 M9MSQ1
Q9VX80 Q9VX80
X2JFU3 X2JFU3

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