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slco1d1 solute carrier organic anion transporter family, member 1D1 [ Danio rerio (zebrafish) ]

Gene ID: 326845, updated on 27-Dec-2024

Summary

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Official Symbol
slco1d1provided by ZNC
Official Full Name
solute carrier organic anion transporter family, member 1D1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5044
See related
Ensembl:ENSDARG00000104108 AllianceGenome:ZFIN:ZDB-GENE-030131-5044
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
slco1c; wu:fe36b05; zgc:163027
Summary
Enables organic anion transmembrane transporter activity. Acts upstream of or within microcystin transport and organic anion transport. Located in plasma membrane. Is expressed in several structures, including alar plate midbrain region; muscle; nervous system; optic vesicle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in bilirubin metabolic disorder and gastrointestinal stromal tumor. Orthologous to human SLCO1B1 (solute carrier organic anion transporter family member 1B1); SLCO1B3 (solute carrier organic anion transporter family member 1B3); and SLCO1B7 (solute carrier organic anion transporter family member 1B7 (putative)). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See slco1d1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (77389667..77432221, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (76004965..76047519, complement)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene NLR family CARD domain-containing protein 3-like Neighboring gene solute carrier organic anion transporter family, member 1F3 Neighboring gene solute carrier organic anion transporter family, member 1E1 Neighboring gene proton myo-inositol cotransporter Neighboring gene si:ch211-266c8.2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zebrafish Oatp1d1 Acts as a Cellular Efflux Transporter of the Anionic Herbicide Bromoxynil. Halbach K, et al. Chem Res Toxicol, 2022 Feb 21. PMID 34990119
  2. Selective interaction of microcystin congeners with zebrafish (Danio rerio) Oatp1d1 transporter. Marić P, et al. Chemosphere, 2021 Nov. PMID 34182632
  3. Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide. Popovic M, et al. J Biol Chem, 2013 Nov 22. PMID 24126916, Free PMC Article
  4. Interaction of environmental steroids with organic anion transporting polypeptide (Oatp1d1) in zebrafish (Danio rerio). Willi RA, et al. Environ Toxicol Chem, 2018 Oct. PMID 30055005
  5. Interaction of environmental contaminants with zebrafish organic anion transporting polypeptide, Oatp1d1 (Slco1d1). Popovic M, et al. Toxicol Appl Pharmacol, 2014 Oct 1. PMID 25088042

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Zebrafish Oatp1d1 Acts as a Cellular Efflux Transporter of the Anionic Herbicide Bromoxynil.
    Title: Zebrafish Oatp1d1 Acts as a Cellular Efflux Transporter of the Anionic Herbicide Bromoxynil.
  2. Selective interaction of microcystin congeners with zebrafish (Danio rerio) Oatp1d1 transporter.
    Title: Selective interaction of microcystin congeners with zebrafish (Danio rerio) Oatp1d1 transporter.
  3. different classes of steroids interact with Oatp1d1 with different activity.
    Title: Interaction of environmental steroids with organic anion transporting polypeptide (Oatp1d1) in zebrafish (Danio rerio).
  4. Zebrafish Oatp1d1 offers new insights into the uptake processes of environmental contaminants.
    Title: Interaction of environmental contaminants with zebrafish organic anion transporting polypeptide, Oatp1d1 (Slco1d1).
  5. detailed characterization of a new Oatp transporter in zebrafish, offering important insights into the functional evolution of the OATP1/Oatp1 family and the physiological role of Oatp1d1.
    Title: Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables organic anion transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within microcystin transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within organic anion transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
solute carrier organic anion transporter family, member 1D1
Names
Oatp1d1
solute carrier anion transporting family member 1d1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001348086.1 → NP_001335015.1  solute carrier organic anion transporter family, member 1D1

    Status: VALIDATED

    Source sequence(s)
    FP236807
    UniProtKB/TrEMBL
    A0A8M9PU70
    Related
    ENSDARP00000139849.2, ENSDART00000158683.3
    Conserved Domains (1) summary
    pfam03137
    Location:16 → 617
    OATP; Organic Anion Transporter Polypeptide (OATP) family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    77389667..77432221 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001089333.1: Suppressed sequence

    Description
    NM_001089333.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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