Pp2B-14D - Protein phosphatase 2B at 14D
Enables calmodulin-dependent protein phosphatase activity. Involved in several processes, including female meiotic nuclear division; regulation of embryonic development; and sleep. Predicted to be part of calcineurin complex. Predicted to be active in cytoplasm. Is expressed in adult head; central nervous system; organism; and presumptive embryonic/larval peripheral nervous system. Used to study cardiomyopathy. Human ortholog(s) of this gene implicated in aortic valve stenosis; developmental and epileptic encephalopathy 91; and schizophrenia. Orthologous to several human genes including PPP3CB (protein phosphatase 3 catalytic subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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