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SMC5 - Structural maintenance of chromosomes 5

Predicted to enable ATP hydrolysis activity; damaged DNA binding activity; and single-stranded DNA binding activity. Involved in DNA damage response. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Is expressed in organism and spermatozoon. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome. Orthologous to human SMC5 (structural maintenance of chromosomes 5). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa