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CG31926 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 326174, updated on 9-Dec-2024

Summary

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Official Symbol
CG31926provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0051926
Locus tag
Dmel_CG31926
See related
AllianceGenome:FB:FBgn0051926
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10872; Dmel\CG31926
Summary
Predicted to enable aspartic-type endopeptidase activity. Involved in egg chorion assembly. Predicted to be active in lysosome. Orthologous to human PGA3 (pepsinogen A3); PGA4 (pepsinogen A4); and PGA5 (pepsinogen A5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG31926 in Genome Data Viewer
Location:
22A2-22A2; 2-3 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1495460..1497071)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1495460..1497071)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44064 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An MMP liberates the Ninjurin A ectodomain to signal a loss of cell adhesion. Zhang S, et al. Genes Dev, 2006 Jul 15. PMID 16815999, Free PMC Article
  2. Drosophila eggshell production: identification of new genes and coordination by Pxt. Tootle TL, et al. PLoS One, 2011. PMID 21637834, Free PMC Article
  3. Reproductive toxicity of polystyrene nanoplastics in Drosophila melanogaster under multi-generational exposure. Tu Q, et al. Chemosphere, 2023 Jul. PMID 37080472
  4. Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins. Colca JR, et al. PLoS One, 2013. PMID 23690925, Free PMC Article
  5. Differential gene expression related to Nora virus infection of Drosophila melanogaster. Cordes EJ, et al. Virus Res, 2013 Aug. PMID 23603562, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in egg chorion assembly IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in egg chorion assembly IGC
Inferred from Genomic Context
more info
 PubMed 
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in egg chorion IGC
Inferred from Genomic Context
more info
 PubMed 
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG31926-PA
CG31926-PB
aspartic-type endopeptidase
NP_001259870.1
NP_722706.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    1495460..1497071
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272941.1 → NP_001259870.1  uncharacterized protein Dmel_CG31926, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259870.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3DMV2, Q9VQ13
    Conserved Domains (2) summary
    pfam00026
    Location:89 → 408
    Asp; Eukaryotic aspartyl protease
    cl11403
    Location:82 → 406
    pepsin_retropepsin_like; Cellular and retroviral pepsin-like aspartate proteases

  2. NM_164419.2 → NP_722706.1  uncharacterized protein Dmel_CG31926, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722706.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3DMV2, Q9VQ13
    Related
    FBpp0077596
    Conserved Domains (2) summary
    pfam00026
    Location:89 → 408
    Asp; Eukaryotic aspartyl protease
    cl11403
    Location:82 → 406
    pepsin_retropepsin_like; Cellular and retroviral pepsin-like aspartate proteases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VQ13 Q9VQ13

Gene LinkOut

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