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CG18858 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 326109, updated on 9-Dec-2024

Summary

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Official Symbol
CG18858provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0042175
Locus tag
Dmel_CG18858
See related
AllianceGenome:FB:FBgn0042175
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
38C.53; Dmel\CG18858
Summary
Enables serine hydrolase activity. Predicted to be involved in lipid metabolic process. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in Norum disease and arteriosclerosis. Orthologous to several human genes including PLA2G15 (phospholipase A2 group XV). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG18858 in Genome Data Viewer
Location:
38C7-38C7; 2-54 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20456847..20459075, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20456847..20459075, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43607 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44980 Neighboring gene Cell division cycle 23 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel regulators of planar cell polarity: a genetic analysis in Drosophila. Weber U, et al. Genetics, 2012 May. PMID 22391484, Free PMC Article
  2. Map position and expression of the genes in the 38 region of Drosophila. Butler H, et al. Genetics, 2001 Aug. PMID 11514449, Free PMC Article
  3. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article
  4. GlycoFly: a database of Drosophila N-linked glycoproteins identified using SPEG--MS techniques. Baycin-Hizal D, et al. J Proteome Res, 2011 Jun 3. PMID 21480662
  5. Protein interaction mapping: a Drosophila case study. Formstecher E, et al. Genome Res, 2005 Mar. PMID 15710747, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine hydrolase activity HDA PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG18858-PA
CG18858-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    20456847..20459075 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273699.1 → NP_001260628.1  uncharacterized protein Dmel_CG18858, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260628.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C3KGK6, Q9I7L9
    Conserved Domains (1) summary
    cl21494
    Location:81 → 405
    Abhydrolase; alpha/beta hydrolases

  2. NM_144443.2 → NP_652700.1  uncharacterized protein Dmel_CG18858, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652700.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C3KGK6, Q9I7L9
    Related
    FBpp0080896
    Conserved Domains (1) summary
    cl21494
    Location:81 → 405
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I7L9 Q9I7L9

Gene LinkOut

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