Cyp1 - Cyclophilin 1

Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in response to oxidative stress. Located in mitochondrion. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut primordium; gut section; and mesoderm. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to several human genes including PPIF (peptidylprolyl isomerase F). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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