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ND-20 - NADH dehydrogenase (ubiquinone) 20 kDa subunit

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to contribute to NADH dehydrogenase activity. Involved in several processes, including determination of adult lifespan; mitochondrial respiratory chain complex I assembly; and regulation of terminal button organization. Part of respiratory chain complex I. Is expressed in several structures, including adult head; adult heart; dorsal pharyngeal muscle cell; embryonic/larval midgut primordium; and gut section. Used to study mitochondrial complex I deficiency and nuclear type mitochondrial complex I deficiency 3. Human ortholog(s) of this gene implicated in developmental disorder of mental health and nuclear type mitochondrial complex I deficiency 3. Orthologous to human NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa