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CG8578 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32540, updated on 9-Dec-2024

Summary

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Official Symbol
CG8578provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030699
Locus tag
Dmel_CG8578
See related
AllianceGenome:FB:FBgn0030699
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8578
Summary
Enables small GTPase binding activity. Involved in adult somatic muscle development. Orthologous to several human genes including LRRFIP2 (LRR binding FLII interacting protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG8578 in Genome Data Viewer
Location:
13F10-13F12; 1-52 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15844476..15847858)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15738509..15741891)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Arginyl-tRNA synthetase Neighboring gene stunted Neighboring gene Ubiquitin like 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The epsilon-subunit of mitochondrial ATP synthase is required for normal spindle orientation during the Drosophila embryonic divisions. Kidd T, et al. Genetics, 2005 Jun. PMID 15834145, Free PMC Article
  2. Myeloid Leukemia Factor Acts in a Chaperone Complex to Regulate Transcription Factor Stability and Gene Expression. Dyer JO, et al. J Mol Biol, 2017 Jun 30. PMID 27984043, Free PMC Article
  3. A pair of centromeric proteins mediates reproductive isolation in Drosophila species. Thomae AW, et al. Dev Cell, 2013 Nov 25. PMID 24239514
  4. The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster. Zhou S, et al. Environ Health Perspect, 2016 Jul. PMID 26859824, Free PMC Article
  5. Toward a comprehensive map of the effectors of rab GTPases. Gillingham AK, et al. Dev Cell, 2014 Nov 10. PMID 25453831, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables small GTPase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in adult somatic muscle development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8578-PA
CG8578-PB
CG8578-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    15844476..15847858
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298374.1 → NP_001285303.1  uncharacterized protein Dmel_CG8578, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285303.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0E4, Q9VXN3
    Conserved Domains (1) summary
    pfam09738
    Location:47 → 321
    DUF2051; Double stranded RNA binding protein (DUF2051)

  2. NM_132854.3 → NP_573082.1  uncharacterized protein Dmel_CG8578, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573082.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0E4, Q9VXN3
    Related
    FBpp0073918
    Conserved Domains (1) summary
    pfam09738
    Location:47 → 321
    DUF2051; Double stranded RNA binding protein (DUF2051)

  3. NM_001298373.1 → NP_001285302.1  uncharacterized protein Dmel_CG8578, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285302.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0E4, Q9VXN3
    Conserved Domains (1) summary
    pfam09738
    Location:47 → 321
    DUF2051; Double stranded RNA binding protein (DUF2051)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VXN3 Q9VXN3

Gene LinkOut

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