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CG9123 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32462, updated on 9-Dec-2024

Summary

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Official Symbol
CG9123provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030629
Locus tag
Dmel_CG9123
See related
AllianceGenome:FB:FBgn0030629
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9123
Summary
Predicted to enable protein kinase inhibitor activity. Predicted to be involved in cell population proliferation and maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be active in nucleolus. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; larval muscle cell; and mesoderm. Orthologous to human PAK1IP1 (PAK1 interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See CG9123 in Genome Data Viewer
Location:
13B6-13B6; 1-50 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15340373..15342117, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15234406..15236150, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene discontinuous actin hexagon Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44998 Neighboring gene Histone deacetylase 6 Neighboring gene uncharacterized protein Neighboring gene pre-mRNA processing factor 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Recent strong positive selection on Drosophila melanogaster HDAC6, a gene encoding a stress surveillance factor, as revealed by population genomic analysis. Svetec N, et al. Mol Biol Evol, 2009 Jul. PMID 19349642
  2. Excess of amino acid substitutions relative to polymorphism between X-linked duplications in Drosophila melanogaster. Thornton K, et al. Mol Biol Evol, 2005 Feb. PMID 15483321
  3. Transcription factor networks in Drosophila melanogaster. Rhee DY, et al. Cell Rep, 2014 Sep 25. PMID 25242320, Free PMC Article
  4. Comprehensive Identification and Alternative Splicing of Microexons in Drosophila. Pang TL, et al. Front Genet, 2021. PMID 33859668, Free PMC Article
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein kinase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell population proliferation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosome biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9123-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    15340373..15342117 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132790.3 → NP_573018.1  uncharacterized protein Dmel_CG9123 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573018.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C5I7K5, Q9VXW4
    Related
    FBpp0073836
    Conserved Domains (3) summary
    COG2319
    Location:60 → 294
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:50 → 85
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:49 → 295
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VXW4 Q9VXW4

Gene LinkOut

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