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taf2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor [ Danio rerio (zebrafish) ]

Gene ID: 324486, updated on 9-Dec-2024

Summary

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Official Symbol
taf2provided by ZNC
Official Full Name
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-3207
See related
Ensembl:ENSDARG00000102307 AllianceGenome:ZFIN:ZDB-GENE-030131-3207
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc30f02; fc56a05; TAFII150; TAFII-150; wu:fc30f02; wu:fc56a05
Summary
Predicted to enable chromatin binding activity and transcription cis-regulatory region binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 40. Orthologous to human TAF2 (TATA-box binding protein associated factor 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See taf2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (9580689..9606284)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (9689787..9715382)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 2 Neighboring gene mal, T cell differentiation protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Identification of 315 genes essential for early zebrafish development. Amsterdam A, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15256591, Free PMC Article
  2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC123088

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
contributes_to RNA polymerase II general transcription initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in transcription initiation at RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIID complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIID complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transcription initiation factor TFIID subunit 2
Names
TAF(II)150
TATA box binding protein (TBP)-associated factor 150kDa
TBP-associated factor 150 kDa
transcription initiation factor TFIID 150 kDa subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003835.2 → NP_001003835.2  transcription initiation factor TFIID subunit 2

    See identical proteins and their annotated locations for NP_001003835.2

    Status: VALIDATED

    Source sequence(s)
    CR854958
    UniProtKB/Swiss-Prot
    Q32PW3, Q5BJ13, Q6DGD5, Q6DRH8
    Related
    ENSDARP00000139157.1, ENSDART00000165565.2
    Conserved Domains (2) summary
    cd09839
    Location:16 → 530
    M1_TAF2; TATA binding protein (TBP) associated factor 2
    pfam13646
    Location:641 → 696
    HEAT_2; HEAT repeats

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    9580689..9606284
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021466622.2 → XP_021322297.1  transcription initiation factor TFIID subunit 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M9NZ39
    Conserved Domains (1) summary
    cd09839
    Location:16 → 530
    M1_TAF2; TATA binding protein (TBP) associated factor 2
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q32PW3.2 GenPept UniProtKB/Swiss-Prot:Q32PW3

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