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Dbct - Dihydrolipoamide branched chain transacylase E2

Predicted to enable acetyltransferase activity and lipoic acid binding activity. Predicted to contribute to branched-chain alpha-keto acid dehydrogenase activity. Involved in L-leucine catabolic process; isoleucine catabolic process; and valine catabolic process. Predicted to be part of branched-chain alpha-ketoacid dehydrogenase complex. Predicted to be active in mitochondrion. Is expressed in adult head; adult heart; embryonic/larval midgut; and organism. Used to study maple syrup urine disease. Human ortholog(s) of this gene implicated in maple syrup urine disease. Orthologous to human DBT (dihydrolipoamide branched chain transacylase E2). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa