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insm1b - insulinoma-associated 1b

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin DNA binding activity. Predicted to be involved in several processes, including enteroendocrine cell differentiation; negative regulation of transcription by RNA polymerase II; and transdifferentiation. Predicted to act upstream of or within cell differentiation and nervous system development. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Is expressed in digestive system; midbrain neural keel; nervous system; olfactory field; and trigeminal placode. Orthologous to human INSM1 (INSM transcriptional repressor 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa