sult1st1 sulfotransferase family 1, cytosolic sulfotransferase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sult1st1provided by ZNC
Official Full Name: sulfotransferase family 1, cytosolic sulfotransferase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2144
See related: Ensembl:ENSDARG00000028275 AllianceGenome:ZFIN:ZDB-GENE-030131-2144
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb98b02; fk46b09; wu:fb98b02; wu:fk46b09
Summary: Enables sulfotransferase activity. Involved in xenobiotic metabolic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including breast cancer; gastrointestinal system cancer (multiple); lung cancer (multiple); reproductive organ cancer (multiple); and urinary bladder cancer. Orthologous to several human genes including SULT1A1 (sulfotransferase family 1A member 1); SULT1A2 (sulfotransferase family 1A member 2); and SULT1A3 (sulfotransferase family 1A member 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: chromosome: 8

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (46499097..46508869, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (46491218..46500978, complement)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fk46b09.x1 (e-PCR)
- UniSTS:201032

fb98b02.x1 (e-PCR)
- UniSTS:203604

fi58b04.y1 (e-PCR)
- UniSTS:197732

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables aryl sulfotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables sulfotransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables sulfotransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within catecholamine metabolic process	IEA Inferred from Electronic Annotation more info
involved_in sulfation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within xenobiotic metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in xenobiotic metabolic process	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytosolic sulfotransferase 1

Names: SULT1 ST1; sulfotransferase family, cytosolic sulfotransferase 1

NP_891986.2

EC 2.8.2.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.