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CG11134 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32334, updated on 9-Dec-2024

Summary

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Official Symbol
CG11134provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030518
Locus tag
Dmel_CG11134
See related
AllianceGenome:FB:FBgn0030518
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
1; Dmel\CG11134
Summary
Predicted to enable methylthioribulose 1-phosphate dehydratase activity and zinc ion binding activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be active in cytoplasm. Is expressed in several structures, including embryonic/larval midgut primordium; epithelial tube; gut section; mesoderm; and visceral mesoderm derivative. Orthologous to human APIP (APAF1 interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG11134 in Genome Data Viewer
Location:
12B4-12B4; 1-45 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13737942..13739177)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13631975..13633210)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene mutagen-sensitive 101 Neighboring gene garnet Neighboring gene Gamma-tubulin ring protein 91 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR42861

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutation of a Drosophila gamma tubulin ring complex subunit encoded by discs degenerate-4 differentially disrupts centrosomal protein localization. Barbosa V, et al. Genes Dev, 2000 Dec 15. PMID 11124805, Free PMC Article
  2. Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila. Parkhitko AA, et al. Genes Dev, 2016 Jun 15. PMID 27313316, Free PMC Article
  3. Collagen secretion screening in Drosophila supports a common secretory machinery and multiple Rab requirements. Ke H, et al. J Genet Genomics, 2018 Jun 1. PMID 29935791
  4. A misexpression screen to identify regulators of Drosophila larval hemocyte development. Stofanko M, et al. Genetics, 2008 Sep. PMID 18757933, Free PMC Article
  5. A genetic interaction map of cell cycle regulators. Billmann M, et al. Mol Biol Cell, 2016 Apr 15. PMID 26912791, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables methylthioribulose 1-phosphate dehydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables methylthioribulose 1-phosphate dehydratase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in L-methionine salvage from methylthioadenosine IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-methionine salvage from methylthioadenosine IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11134-PA
CG11134-PB
transcript 1
NP_001259530.1
NP_572916.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    13737942..13739177
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272601.1 → NP_001259530.1  uncharacterized protein Dmel_CG11134, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259530.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VY93
    UniProtKB/TrEMBL
    M9PEI9
    Conserved Domains (1) summary
    TIGR03328
    Location:18 → 216
    salvage_mtnB; methylthioribulose-1-phosphate dehydratase

  2. NM_132688.4 → NP_572916.1  uncharacterized protein Dmel_CG11134, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572916.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VY93
    UniProtKB/TrEMBL
    M9PEI9
    Related
    FBpp0073649
    Conserved Domains (1) summary
    TIGR03328
    Location:18 → 216
    salvage_mtnB; methylthioribulose-1-phosphate dehydratase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PEI9 M9PEI9
Q9VY93.1 Q9VY93

Gene LinkOut

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