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DET_RS04250 thymidylate synthase [ Dehalococcoides mccartyi 195 ]

Gene ID: 3229916, updated on 11-Dec-2024

Summary

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Gene symbol
DET_RS04250
Gene description
thymidylate synthase
Locus tag
DET_RS04250
Gene type
protein coding
Organism
Dehalococcoides mccartyi 195 (strain: 195, type-material: type strain of Dehalococcoides mccartyi)
Lineage
Bacteria; Bacillati; Chloroflexota; Dehalococcoidia; Dehalococcoidales; Dehalococcoidaceae; Dehalococcoides
Old locus tag
DET0819
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Genomic context

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Sequence:
NC_002936.3 (748199..748852, complement)

NC_002936.3Genomic Context describing neighboring genes Neighboring gene ABC transporter ATP-binding protein Neighboring gene tRNA-Lys Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002936.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Thymidylate synthase structure, function and implication in drug discovery. Costi MP, et al. Curr Med Chem, 2005. PMID 16178783
  2. Pairwise specificity and sequential binding in enzyme catalysis: thymidylate synthase. Finer-Moore JS, et al. Biochemistry, 1990 Jul 31. PMID 2223755
  3. Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site. Wang Z, et al. J Am Chem Soc, 2013 May 22. PMID 23611499, Free PMC Article
  4. Structure-based studies on species-specific inhibition of thymidylate synthase. Costi MP, et al. Biochim Biophys Acta, 2002 Jul 18. PMID 12084462
  5. Genome sequence of the PCE-dechlorinating bacterium Dehalococcoides ethenogenes. Seshadri R, et al. Science, 2005 Jan 7. PMID 15637277

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
thymidylate synthase
WP_010936547.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002936.3 Reference assembly

    Range
    748199..748852 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010936547.1 thymidylate synthase [Dehalococcoides mccartyi]

    See identical proteins and their annotated locations for WP_010936547.1

    UniProtKB/TrEMBL
    Q3Z8A3
Nucleotide Protein
Heading Accession and Version