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Ype Yippee [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32295, updated on 4-Jan-2025

Summary

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Official Symbol
Ypeprovided by FlyBase
Official Full Name
Yippeeprovided by FlyBase
Primary source
FLYBASE:FBgn0288857
Locus tag
Dmel_CG1989
See related
AllianceGenome:FB:FBgn0288857
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG1989; Dmel\CG1989; eb; s; sable; YIPPEE
Summary
Involved in adult chitin-containing cuticle pigmentation; chaeta morphogenesis; and imaginal disc-derived wing morphogenesis. Predicted to be part of ubiquitin ligase complex. Is expressed in organism. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Ype in Genome Data Viewer
Location:
11F1-11F1; 1-43 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13385914..13387417, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13279947..13281450, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Rbp1-like Neighboring gene Tim9a Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44620

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. "A fly appeared": sable, a classic Drosophila mutation, maps to Yippee, a gene affecting body color, wings, and bristles. Dean DM, et al. G3 (Bethesda), 2022 May 6. PMID 35266526, Free PMC Article
  2. The Drosophila gene Yippee reveals a novel family of putative zinc binding proteins highly conserved among eukaryotes. Roxström-Lindquist K, et al. Insect Mol Biol, 2001 Feb. PMID 11240639
  3. Genetic Control of Dopa Oxidase Activity in Drosophila Melanogaster. I. Analysis of Wild Type, Sable, Suppressor-of-Sable and Suppressed Sable Strains. Lewis HW. Genetics, 1960 Sep. PMID 17247994, Free PMC Article
  4. Frameshift mutations of YPEL3 alter the sensory circuit function in Drosophila. Kim JH, et al. Dis Model Mech, 2020 Jun 3. PMID 32461240, Free PMC Article
  5. Structure and expression of wild-type and suppressible alleles of the Drosophila purple gene. Kim N, et al. Genetics, 1996 Apr. PMID 8846895, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables metal ion binding NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in adult chitin-containing cuticle pigmentation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in chaeta morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in imaginal disc-derived wing morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
part_of ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
yippee
Names
CG1989-PA
CG1989-PB
Ype-PA
Ype-PB
ebonised
ebonized
sable

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    13385914..13387417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132654.4 → NP_572882.1  yippee, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572882.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XZF0
    UniProtKB/TrEMBL
    D3DMZ2
    Related
    FBpp0073620
    Conserved Domains (1) summary
    cl13152
    Location:15 → 107
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

  2. NM_001038752.2 → NP_001033841.1  yippee, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033841.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MSV1
    Conserved Domains (1) summary
    cl13152
    Location:15 → 90
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MSV1 Q8MSV1
Q9XZF0.1 Q9XZF0

Gene LinkOut

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