SelG Selenoprotein G [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: SelGprovided by FlyBase
Official Full Name: Selenoprotein Gprovided by FlyBase
Primary source: FLYBASE:FBgn0030350
Locus tag: Dmel_CG1844
See related: AllianceGenome:FB:FBgn0030350
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:GH03581; CG1844; Dmel\CG1844; dselG; dselK; dSelK; G-rich; SelK
Summary: Involved in several processes, including determination of adult lifespan; endoplasmic reticulum calcium ion homeostasis; and regulation of gastrulation. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (11887284..11888240)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (11781317..11782273)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

SelK elevates release of Ca2+ from endoplasmic reticulum by upregulating expression of inositol 1,4,5-tris-phosphate receptor.
Title: Selenoprotein dSelK in Drosophila elevates release of Ca2+ from endoplasmic reticulum by upregulating expression of inositol 1,4,5-tris-phosphate receptor.
G-rich is the first selenoprotein identified in the Golgi apparatus.
Title: G-rich, a Drosophila selenoprotein, is a Golgi-resident type III membrane protein.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in blastoderm segmentation	IDA Inferred from Direct Assay more info	PubMed
involved_in calcium ion transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell redox homeostasis	TAS Traceable Author Statement more info	PubMed
involved_in determination of adult lifespan	IDA Inferred from Direct Assay more info	PubMed
involved_in embryo development ending in birth or egg hatching	IDA Inferred from Direct Assay more info	PubMed
involved_in embryonic development via the syncytial blastoderm	IDA Inferred from Direct Assay more info	PubMed
involved_in endoplasmic reticulum calcium ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum calcium ion homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of gastrulation	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in intracellular membrane-bounded organelle	IDA Inferred from Direct Assay more info	PubMed