U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

hnrnpaba heterogeneous nuclear ribonucleoprotein A/Ba [ Danio rerio (zebrafish) ]

Gene ID: 321466, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
hnrnpabaprovided by ZNC
Official Full Name
heterogeneous nuclear ribonucleoprotein A/Baprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-185
See related
Ensembl:ENSDARG00000007960 AllianceGenome:ZFIN:ZDB-GENE-030131-185
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
hnrpab; hnrnpab; zeh1271; sqd-likeA; hm:zeh1271; wu:fa18g02; wu:fb07b06; wu:fb16c05
Summary
Predicted to enable RNA binding activity. Predicted to be involved in regulation of gene expression. Predicted to be located in chromatin. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Is expressed in several structures, including EVL; digestive system; fin; nervous system; and periderm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human HNRNPAB (heterogeneous nuclear ribonucleoprotein A/B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See hnrnpaba in Genome Data Viewer
Location:
chromosome: 14
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (6962344..6966131)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (6655553..6659404)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene receptor for activated C kinase 1 Neighboring gene NME/NM23 family member 5 Neighboring gene eukaryotic translation initiation factor 4E binding protein 3, like Neighboring gene heterogeneous nuclear ribonucleoprotein H1 Neighboring gene RUN and FYVE domain containing 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The expression of CPEB proteins is sequentially regulated during zebrafish oogenesis and embryogenesis. O'Connell ML, et al. Mol Reprod Dev, 2014 Apr. PMID 24474627
  2. Impacts of triclosan exposure on zebrafish early-life stage: Toxicity and acclimation mechanisms. Falisse E, et al. Aquat Toxicol, 2017 Aug. PMID 28605648
  3. Analysis of the zebrafish proteome during embryonic development. Lucitt MB, et al. Mol Cell Proteomics, 2008 May. PMID 18212345, Free PMC Article
  4. Genome wide analysis of 3' UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish. Vejnar CE, et al. Genome Res, 2019 Jul. PMID 31227602, Free PMC Article
  5. Analysis of protein expression in developmental toxicity induced by MeHg in zebrafish. Cuello S, et al. Analyst, 2012 Nov 21. PMID 23014190

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of macromolecule biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of RNA metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
heterogeneous nuclear ribonucleoprotein A/Ba
Names
heterogeneous nuclear ribonucleoprotein A/B

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212587.3 → NP_997752.2  heterogeneous nuclear ribonucleoprotein A/Ba

    See identical proteins and their annotated locations for NP_997752.2

    Status: VALIDATED

    Source sequence(s)
    BC066454
    UniProtKB/TrEMBL
    A0A8N7XJ29, F8W4E3, Q4QRD8, Q6NYU8
    Related
    ENSDARP00000124217.2, ENSDART00000148447.3
    Conserved Domains (3) summary
    cd12584
    Location:149 → 228
    RRM2_hnRNPAB; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
    cd12757
    Location:70 → 144
    RRM1_hnRNPAB; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
    pfam08143
    Location:1 → 69
    CBFNT; CBFNT (NUC161) domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    6962344..6966131
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169577.3 → XP_005169634.1  heterogeneous nuclear ribonucleoprotein A/Ba isoform X1

    UniProtKB/TrEMBL
    A0A8M2BHF1
    Conserved Domains (3) summary
    cd12584
    Location:149 → 228
    RRM2_hnRNPAB; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
    cd12757
    Location:70 → 144
    RRM1_hnRNPAB; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
    pfam08143
    Location:1 → 69
    CBFNT; CBFNT (NUC161) domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools