FucT6 alpha1,6-fucosyltransferase [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: FucT6provided by FlyBase
Official Full Name: alpha1,6-fucosyltransferaseprovided by FlyBase
Primary source: FLYBASE:FBgn0030327
Locus tag: Dmel_CG2448
See related: AllianceGenome:FB:FBgn0030327
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 6-FucT; BEST:CK00490; CG2448; CK00490; dalpha6Fut; Dm alpha1; Dmel\CG2448; Fuc-TVIII
Summary: Enables alpha-(1->6)-fucosyltransferase activity. Predicted to be involved in GDP-L-fucose metabolic process; N-glycan fucosylation; and protein N-linked glycosylation via asparagine. Predicted to be located in Golgi cisterna membrane. Is expressed in several structures, including adult head; embryonic head sensory system; embryonic hindgut; embryonic labial sensory complex; and ganglia. Orthologous to human FUT8 (fucosyltransferase 8). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (11706575..11709951, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (11600608..11603984, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables alpha-(1->6)-fucosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alpha-(1->6)-fucosyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables glycoprotein 6-alpha-L-fucosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycoprotein 6-alpha-L-fucosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in GDP-L-fucose metabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in N-glycan fucosylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein N-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein N-linked glycosylation via asparagine	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi cisterna membrane	IEA Inferred from Electronic Annotation more info

NP_572740.1

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The following sections contain reference sequences that belong to a specific genome build. Explain