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mcmbp minichromosome maintenance complex binding protein [ Danio rerio (zebrafish) ]

Gene ID: 321119, updated on 9-Dec-2024

Summary

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Official Symbol
mcmbpprovided by ZNC
Official Full Name
minichromosome maintenance complex binding proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9676
See related
Ensembl:ENSDARG00000055314 AllianceGenome:ZFIN:ZDB-GENE-030131-9676
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb136; MCM-BP; sb:cb136; c10orf119; zgc:55981; wu:fi19h07
Summary
Predicted to enable chromatin binding activity. Predicted to be involved in DNA-templated DNA replication and sister chromatid cohesion. Predicted to act upstream of or within DNA replication and cell division. Predicted to be located in nucleus. Predicted to be part of MCM complex. Is expressed in several structures, including alar plate midbrain region; blood; immature eye; nervous system; and ventral mesoderm. Orthologous to human MCMBP (minichromosome maintenance complex binding protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See mcmbp in Genome Data Viewer
Location:
chromosome: 13
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (25535043..25548882, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (25404593..25418432, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene TIA1 cytotoxic granule-associated RNA binding protein-like 1 Neighboring gene BCL2 associated athanogene 3 Neighboring gene inositol polyphosphate-5-phosphatase F Neighboring gene SEC23 interacting protein Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Characterization of a BAC library from channel catfish Ictalurus punctatus: indications of high levels of chromosomal reshuffling among teleost genomes. Wang S, et al. Mar Biotechnol (NY), 2007 Nov-Dec. PMID 17671813
  2. Identification and Expression Analysis of the Complete Family of Zebrafish pkd Genes. England SJ, et al. Front Cell Dev Biol, 2017. PMID 28271061, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA replication IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA-templated DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA-templated DNA replication ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in sister chromatid cohesion ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of MCM complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
mini-chromosome maintenance complex-binding protein
Names
MCM-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212578.1 → NP_997743.1  mini-chromosome maintenance complex-binding protein

    See identical proteins and their annotated locations for NP_997743.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044562
    Related
    ENSDARP00000130337.2, ENSDART00000168099.2
    Conserved Domains (1) summary
    pfam09739
    Location:36 → 616
    MCM_bind; Mini-chromosome maintenance replisome factor

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    25535043..25548882 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068224922.1 → XP_068081023.1  mini-chromosome maintenance complex-binding protein isoform X2

    UniProtKB/TrEMBL
    A0A8M2B3P0

  2. XM_068224921.1 → XP_068081022.1  mini-chromosome maintenance complex-binding protein isoform X1

    UniProtKB/Swiss-Prot
    A8E7D0, Q803A6
    Related
    ENSDARP00000120704.1, ENSDART00000135788.3
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q803A6.2 GenPept UniProtKB/Swiss-Prot:Q803A6

Gene LinkOut

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