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wdr3 WD repeat domain 3 [ Danio rerio (zebrafish) ]

Gene ID: 321058, updated on 9-Dec-2024

Summary

Official Symbol
wdr3provided by ZNC
Official Full Name
WD repeat domain 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9830
See related
Ensembl:ENSDARG00000011079 AllianceGenome:ZFIN:ZDB-GENE-030131-9830
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:cb42; wu:fb92b07
Summary
Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; midbrain; and retina. Human ortholog(s) of this gene implicated in papillary thyroid carcinoma. Orthologous to human WDR3 (WD repeat domain 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See wdr3 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (20853908..20872565)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (21043039..21061696)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene terminal nucleotidyltransferase 5C Neighboring gene ganglioside induced differentiation associated protein 2 Neighboring gene uncharacterized LOC137496517 Neighboring gene T-box transcription factor 15

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables snoRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of Pwp2p-containing subcomplex of 90S preribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
WD repeat-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198873.1NP_942574.1  WD repeat-containing protein 3

    See identical proteins and their annotated locations for NP_942574.1

    Status: PROVISIONAL

    Source sequence(s)
    BC057490
    UniProtKB/TrEMBL
    Q6PFM8
    Related
    ENSDARP00000023281.8, ENSDART00000003648.10
    Conserved Domains (5) summary
    COG2319
    Location:57692
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:400697
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    pfam04003
    Location:799900
    Utp12; Dip2/Utp12 Family
    sd00039
    Location:452487
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:35136
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    20853908..20872565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)