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Or10a Odorant receptor 10a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32086, updated on 9-Dec-2024

Summary

Official Symbol
Or10aprovided by FlyBase
Official Full Name
Odorant receptor 10aprovided by FlyBase
Primary source
FLYBASE:FBgn0030298
Locus tag
Dmel_CG17867
See related
AllianceGenome:FB:FBgn0030298
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
10a; 10B.1; CG17867; Dmel\CG17867; DOR92; Gr10a; OR10a
Summary
Enables ionotropic olfactory receptor activity and ligand-gated calcium channel activity. Involved in calcium ion transmembrane transport and detection of chemical stimulus involved in sensory perception of smell. Located in plasma membrane. Is expressed in adult olfactory receptor neuron Or10a; antennal basiconic sensillum ab1; and antennal lobe glomerulus DL1. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Or10a in Genome Data Viewer
Location:
10B10-10B10; 1-34 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11413467..11417422, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11309613..11311455, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 10b Neighboring gene Gustatory receptor 10a Neighboring gene Glutamine synthetase 2 Neighboring gene Ecotropic viral integration site 5 Neighboring gene Sphingosine kinase 1

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ionotropic olfactory receptor activity HDA PubMed 
enables ionotropic olfactory receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables ligand-gated calcium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
enables ligand-gated monoatomic cation channel activity IDA
Inferred from Direct Assay
more info
PubMed 
enables odorant binding IEA
Inferred from Electronic Annotation
more info
 
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in dendrite membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IC
Inferred by Curator
more info
PubMed 

General protein information

Preferred Names
odorant receptor 10a
Names
CG17867-PB
Or10a-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11413467..11417422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078567.5NP_511122.1  odorant receptor 10a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_511122.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VYZ1
    UniProtKB/TrEMBL
    E2E510, E2E519, E2E522, E2E528, E2E536, E2E543, E2E547, E2E569, E2E578, E2E5A1, E2E5B5, E2E5D4, E2E5H6
    Related
    FBpp0312370
    Conserved Domains (1) summary
    pfam02949
    Location:70396
    7tm_6; 7tm Odorant receptor