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rtv retroactive [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32056, updated on 9-Dec-2024

Summary

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Official Symbol
rtvprovided by FlyBase
Official Full Name
retroactiveprovided by FlyBase
Primary source
FLYBASE:FBgn0261277
Locus tag
Dmel_CG1397
See related
AllianceGenome:FB:FBgn0261277
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
1; CG1397; Dmel\CG1397; l(1)10Ag; l(1)G13; l(1)L1; L1; Rtv
Summary
Involved in chitin-based embryonic cuticle biosynthetic process and regulation of tube diameter, open tracheal system. Is expressed in cephalopharyngeal skeleton; embryonic/larval tracheal section; and epidermal cell. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See rtv in Genome Data Viewer
Location:
10A8-10A8; 1-33 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11152484..11153990, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11046517..11048023, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ran Neighboring gene l(3)mbt interacting protein 1 Neighboring gene Dynein light intermediate chain Neighboring gene uncharacterized protein Neighboring gene Antennal dehydrogenase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila, Chitin and Insect Pest Management. Wang Y, et al. Curr Pharm Des, 2020. PMID 32693764
  2. Specificity of embryonic lethal mutations in Drosophila analyzed in germ line clones. Wieschaus E, et al. Rouxs Arch Dev Biol, 1986 Jan. PMID 28305278
  3. Trynity models a tube valve in the Drosophila larval airway system. Wang Y, et al. Dev Biol, 2018 May 15. PMID 29518377
  4. Genetic control of cuticle formation during embryonic development of Drosophila melanogaster. Ostrowski S, et al. Genetics, 2002 May. PMID 12019232, Free PMC Article
  5. Drosophila Knickkopf and Retroactive are needed for epithelial tube growth and cuticle differentiation through their specific requirement for chitin filament organization. Moussian B, et al. Development, 2006 Jan. PMID 16339194

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in chitin-based embryonic cuticle biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in open tracheal system development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of voltage-gated potassium channel activity IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of synaptic transmission, cholinergic IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of tube architecture, open tracheal system IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of tube diameter, open tracheal system IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sleep IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
retroactive
Names
CG1397-PA
CG1397-PB
CG1397-PC
CG1397-PD
rtv-PA
rtv-PB
rtv-PC
rtv-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11152484..11153990 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298185.1 → NP_001285114.1  retroactive, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285114.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    M9PJI2, Q9VZ21
    UniProtKB/TrEMBL
    B4F5Z0
    Conserved Domains (1) summary
    pfam17064
    Location:26 → 147
    QVR; Sleepless protein

  2. NM_001272513.2 → NP_001259442.1  retroactive, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259442.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    M9PJI2, Q9VZ21
    UniProtKB/TrEMBL
    B4F5Z0
    Conserved Domains (1) summary
    pfam17064
    Location:26 → 147
    QVR; Sleepless protein

  3. NM_132465.4 → NP_572693.1  retroactive, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572693.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    M9PJI2, Q9VZ21
    UniProtKB/TrEMBL
    B4F5Z0
    Related
    FBpp0073326
    Conserved Domains (1) summary
    pfam17064
    Location:26 → 147
    QVR; Sleepless protein

  4. NM_001272514.2 → NP_001259443.1  retroactive, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259443.1

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PJI2 M9PJI2
Q9VZ21 Q9VZ21
Q9VZ21.1

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