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Hsp60A - Heat shock protein 60A

Predicted to enable ATP hydrolysis activity and protein-folding chaperone binding activity. Involved in cellular response to heat and mitochondrion organization. Located in mitochondrial inner membrane. Is expressed in several structures, including adult head; adult heart; dorsal pharyngeal muscle cell; embryonic/larval midgut primordium; and gut section. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autistic disorder; glucose intolerance; hereditary spastic paraplegia (multiple); and hypomyelinating leukodystrophy 4. Orthologous to human HSPD1 (heat shock protein family D (Hsp60) member 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa