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CG1582 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32021, updated on 4-Jan-2025

Summary

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Official Symbol
CG1582provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030246
Locus tag
Dmel_CG1582
See related
AllianceGenome:FB:FBgn0030246
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg1582; DHX57; Dmel\CG1582
Summary
Predicted to enable RNA binding activity and helicase activity. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval midgut primordium; head mesoderm; and trunk mesoderm. Orthologous to human DHX57 (DExH-box helicase 57). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG1582 in Genome Data Viewer
Location:
9F8-9F8; 1-33 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10894747..10899302, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10788780..10793335, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45617 Neighboring gene long non-coding RNA:CR44524 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identical functional organization of nonpolytene and polytene chromosomes in Drosophila melanogaster. Vatolina TY, et al. PLoS One, 2011. PMID 22022482, Free PMC Article
  2. DDX3X and specific initiation factors modulate FMR1 repeat-associated non-AUG-initiated translation. Linsalata AE, et al. EMBO Rep, 2019 Sep. PMID 31347257, Free PMC Article
  3. The Drosophila Translational Control Element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes. Katzenberger RJ, et al. PLoS One, 2012. PMID 22984601, Free PMC Article
  4. Tracing the origin of the compensasome: evolutionary history of DEAH helicase and MYST acetyltransferase gene families. Sanjuán R, et al. Mol Biol Evol, 2001 Mar. PMID 11230534
  5. Characteristics of molecular-genetic organization of intercalary heterochromatin band 10A1-2 in X chromosome of Drosophila melanogaster. Babenko VN, et al. Dokl Biochem Biophys, 2009 Jan-Feb. PMID 19341102

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA helicase activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG1582-PA
CG1582-PB
NP_001285098.1
NP_572663.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    10894747..10899302 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298169.1 → NP_001285098.1  uncharacterized protein Dmel_CG1582, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285098.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VZ55
    Conserved Domains (8) summary
    smart00490
    Location:781 → 871
    HELICc; helicase superfamily c-terminal domain
    smart00847
    Location:948 → 1029
    HA2; Helicase associated domain (HA2) Add an annotation
    COG1643
    Location:419 → 1206
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
    cd00046
    Location:471 → 619
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00642
    Location:250 → 272
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    pfam05773
    Location:284 → 360
    RWD; RWD domain
    pfam07717
    Location:1070 → 1212
    OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
    cl21463
    Location:123 → 154
    UBA_like_SF; UBA domain-like superfamily

  2. NM_132435.2 → NP_572663.1  uncharacterized protein Dmel_CG1582, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572663.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VZ55
    Related
    FBpp0073259
    Conserved Domains (8) summary
    smart00490
    Location:781 → 871
    HELICc; helicase superfamily c-terminal domain
    smart00847
    Location:948 → 1029
    HA2; Helicase associated domain (HA2) Add an annotation
    COG1643
    Location:419 → 1206
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
    cd00046
    Location:471 → 619
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00642
    Location:250 → 272
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    pfam05773
    Location:284 → 360
    RWD; RWD domain
    pfam07717
    Location:1070 → 1212
    OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
    cl21463
    Location:123 → 154
    UBA_like_SF; UBA domain-like superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VZ55 Q9VZ55

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