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sofe sister of feo [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32016, updated on 9-Dec-2024

Summary

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Official Symbol
sofeprovided by FlyBase
Official Full Name
sister of feoprovided by FlyBase
Primary source
FLYBASE:FBgn0030242
Locus tag
Dmel_CG1655
See related
AllianceGenome:FB:FBgn0030242
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG1655; Dmel\CG1655
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in mitotic spindle midzone assembly. Predicted to be active in cytoplasm and mitotic spindle midzone. Is expressed in wing hinge primordium and wing pouch. Orthologous to human PRC1 (protein regulator of cytokinesis 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See sofe in Genome Data Viewer
Location:
9F5-9F5; 1-33 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10855000..10857413, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10749033..10751446, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene fascetto Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Feo, the Drosophila homolog of PRC1, is required for central-spindle formation and cytokinesis. Vernì F, et al. Curr Biol, 2004 Sep 7. PMID 15341744
  2. Characteristics of molecular-genetic organization of intercalary heterochromatin band 10A1-2 in X chromosome of Drosophila melanogaster. Babenko VN, et al. Dokl Biochem Biophys, 2009 Jan-Feb. PMID 19341102
  3. The genetics of egg retention and fertilization success in Drosophila: One step closer to understanding the transition from facultative to obligate viviparity. Horváth B, et al. Evolution, 2018 Feb. PMID 29265369
  4. X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila. Legube G, et al. Genes Dev, 2006 Apr 1. PMID 16547175, Free PMC Article
  5. Post-mating gene expression profiles of female Drosophila melanogaster in response to time and to four male accessory gland proteins. McGraw LA, et al. Genetics, 2008 Jul. PMID 18562649, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic spindle midzone assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitotic spindle midzone IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in spindle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sister of feo
Names
CG1655-PA
CG1655-PB
sofe-PA
sofe-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    10855000..10857413 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298163.1 → NP_001285092.1  sister of feo, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285092.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q961S2, Q9VZ61
    Conserved Domains (1) summary
    pfam03999
    Location:36 → 598
    MAP65_ASE1; Microtubule associated protein (MAP65/ASE1 family)

  2. NM_132431.3 → NP_572659.2  sister of feo, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572659.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q961S2, Q9VZ61
    Related
    FBpp0073265
    Conserved Domains (1) summary
    pfam03999
    Location:36 → 598
    MAP65_ASE1; Microtubule associated protein (MAP65/ASE1 family)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q961S2 Q961S2
Q9VZ61 Q9VZ61

Gene LinkOut

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