PPP4R2r Protein phosphatase 4 regulatory subunit 2-related protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: PPP4R2rprovided by FlyBase
Official Full Name: Protein phosphatase 4 regulatory subunit 2-related proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0030208
Locus tag: Dmel_CG2890
See related: AllianceGenome:FB:FBgn0030208
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:LD29930; CG2890; Dmel\CG2890; PP4R; PP4r2; PP4R2; PP4R2r; Ppp4R2; PPP4R2; R2
Summary: Predicted to enable protein phosphatase regulator activity. Involved in mitotic cell cycle; negative regulation of peptidoglycan recognition protein signaling pathway; and negative regulation of smoothened signaling pathway. Located in chromosome, centromeric region. Part of protein phosphatase 4 complex. Orthologous to human PPP4R2 (protein phosphatase 4 regulatory subunit 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (10478838..10481943)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (10372871..10375976)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein phosphatase regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein phosphatase regulator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mitotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of peptidoglycan recognition protein signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of smoothened signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chromosome, centromeric region	IPI Inferred from Physical Interaction more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of protein phosphatase 4 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of protein phosphatase 4 complex	IDA Inferred from Direct Assay more info	PubMed
part_of protein phosphatase 4 complex	IEA Inferred from Electronic Annotation more info

Names: CG2890-PA; CG2890-PB; CG2890-PC; CG2890-PD; PP4 regulatory subunit; PPP4R2r-PA; PPP4R2r-PB; PPP4R2r-PC; PPP4R2r-PD

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The following sections contain reference sequences that belong to a specific genome build. Explain