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Rsph9 Radial spoke head protein 9 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 318950, updated on 4-Jan-2025

Summary

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Official Symbol
Rsph9provided by FlyBase
Official Full Name
Radial spoke head protein 9provided by FlyBase
Primary source
FLYBASE:FBgn0051803
Locus tag
Dmel_CG31803
See related
AllianceGenome:FB:FBgn0051803
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:AT29119; CG31803; Dmel\CG31803; dRSPH9
Summary
Involved in axoneme assembly. Predicted to be active in axoneme. Is expressed in adult head; spermatogonium; and spermatozoon. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 12. Orthologous to human RSPH9 (radial spoke head component 9). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Rsph9 in Genome Data Viewer
Location:
36C7-36C7; 2-53 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (17411649..17412633, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (17411649..17412633, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Cytoplasmic linker protein 190 Neighboring gene RNA polymerase II subunit J Neighboring gene uncharacterized protein Neighboring gene Dorsal-related immunity factor Neighboring gene long non-coding RNA:CR44409 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RSBP15 interacts with and stabilizes dRSPH3 during sperm axoneme assembly in Drosophila. Wang Y, et al. J Genet Genomics, 2019 Jun 20. PMID 31281031
  2. Transposition of the vertebrate Tol2 transposable element in Drosophila melanogaster. Urasaki A, et al. Gene, 2008 Dec 1. PMID 18775483
  3. Structure and molecular basis of spermatid elongation in the Drosophila testis. Huang Q, et al. Open Biol, 2023 Nov. PMID 37935354, Free PMC Article
  4. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
  5. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in axoneme assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in axoneme assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cilium movement involved in cell motility IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in motile cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in axoneme IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
radial spoke head protein 9
Names
CG31803-PA
Rsph9-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    17411649..17412633 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165215.1 → NP_724049.1  radial spoke head protein 9 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724049.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T3V7
    Related
    FBpp0080563, FBtr0081010
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T3V7 Q8T3V7

Gene LinkOut

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