Prosbeta5R2 Proteasome beta5 subunit-related 2 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Prosbeta5R2provided by FlyBase
Official Full Name: Proteasome beta5 subunit-related 2provided by FlyBase
Primary source: FLYBASE:FBgn0051742
Locus tag: Dmel_CG31742
See related: AllianceGenome:FB:FBgn0051742
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 31742; anon-AE003657.1; beta5R2; CG31742; Dmel\CG31742
Summary: Predicted to enable endopeptidase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome core complex, beta-subunit complex. Predicted to be active in cytosol and nucleus. Orthologous to several human genes including PSMB5 (proteasome 20S subunit beta 5). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (17990418..17991951)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (17990418..17991951)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables endopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables endopeptidase activity	ISS Inferred from Sequence or Structural Similarity more info
enables threonine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in proteolysis involved in protein catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome core complex	IEA Inferred from Electronic Annotation more info
part_of proteasome core complex, beta-subunit complex	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome core complex, beta-subunit complex	ISS Inferred from Sequence or Structural Similarity more info

Names: AE003657 - proteasome beta subunit; CG31742-PA; CG31742-PB; Prosbeta5R2-PA; Prosbeta5R2-PB

NP_001286022.1

NP_724081.1

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The following sections contain reference sequences that belong to a specific genome build. Explain