COX6CL Cytochrome c oxidase subunit 6C-like [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: COX6CLprovided by FlyBase
Official Full Name: Cytochrome c oxidase subunit 6C-likeprovided by FlyBase
Primary source: FLYBASE:FBgn0051644
Locus tag: Dmel_CG31644
See related: AllianceGenome:FB:FBgn0051644
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:AT20031; CG31644; Dmel\CG31644
Summary: Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial membrane. Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrial inner membrane. Is expressed in adult head and spermatozoon. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: 25F5-25F5; 2-17 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (5817890..5818443, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (5817890..5818443, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, cytochrome c to oxygen	IC Inferred by Curator more info

Component	Evidence Code	Pubs
is_active_in mitochondrial inner membrane	IC Inferred by Curator more info
located_in mitochondrial membrane	ISS Inferred from Sequence or Structural Similarity more info
part_of respiratory chain complex IV	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: cytochrome c oxidase subunit 6C-like

Names: CG31644-PA; CG31644-PB; CG31644-PC; COX6CL-PA; COX6CL-PB; COX6CL-PC

NP_001285640.1

unusual splice

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033779.5 Reference assembly

Range

5817890..5818443 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001298710.1 → NP_001285639.1 cytochrome c oxidase subunit 6C-like, isoform B [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001285639.1

Status: REVIEWED

UniProtKB/TrEMBL

X2J713

Conserved Domains (1) summary

cl02795
Location:5 → 71

Cyt_c_Oxidase_VIc; Cytochrome c oxidase subunit VIc. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...
NM_164663.3 → NP_723121.1 cytochrome c oxidase subunit 6C-like, isoform A [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_723121.1

Status: REVIEWED

UniProtKB/TrEMBL

Q8T970

Related

FBpp0078790

Conserved Domains (1) summary

cd00927
Location:4 → 73

Cyt_c_Oxidase_VIc; Cytochrome c oxidase subunit VIc. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...
NM_001298711.1 → NP_001285640.1 cytochrome c oxidase subunit 6C-like, isoform C [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001285640.1

Status: REVIEWED

UniProtKB/TrEMBL

X2JD93

Conserved Domains (1) summary

cd00927
Location:9 → 76

Cyt_c_Oxidase_VIc; Cytochrome c oxidase subunit VIc. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...