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dpy dumpy [ Drosophila melanogaster (fruit fly) ]

Gene ID: 318824, updated on 2-Nov-2024

Summary

Official Symbol
dpyprovided by FlyBase
Official Full Name
dumpyprovided by FlyBase
Primary source
FLYBASE:FBgn0053196
Locus tag
Dmel_CG33196
See related
AllianceGenome:FB:FBgn0053196
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:SD02173; CG15637; CG31724; CG31725; CG31726; CG31727; CG31964; CG31965; CG31966; CG31967; CG31968; CG33000; CG33086; CG33196; CR33195; CT35799; Dmel\CG33196; dmFBN2; dp; Dp; DP; Dpy; DPY; l(2)24Fd; Mur24F; olv[D]; Q8IQ18_DROME; SP460
Summary
Predicted to be an extracellular matrix structural constituent. Involved in several processes, including chitin-based cuticle attachment to epithelium; chitin-based embryonic cuticle biosynthetic process; and imaginal disc-derived wing morphogenesis. Predicted to be located in extracellular matrix. Is expressed in several structures, including epithelial tube; gut section; longitudinal vein; nephrocyte; and organism subdivision. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See dpy in Genome Data Viewer
Location:
24F4-25A1; 2-13 cM
Exon count:
85
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4477462..4614300, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4477462..4614300, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Parkin Interacting Substrate Neighboring gene FIG4 phosphoinositide 5-phosphatase Neighboring gene inebriated Neighboring gene long non-coding RNA:CR43716 Neighboring gene Heterochromatin protein 6 Neighboring gene long non-coding RNA:CR44609 Neighboring gene long non-coding RNA:CR45452

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
dumpy
Names
CG33196-PAA
CG33196-PI
CG33196-PJ
CG33196-PM
CG33196-PO
CG33196-PP
CG33196-PQ
CG33196-PR
CG33196-PS
CG33196-PT
CG33196-PU
CG33196-PV
CG33196-PW
CG33196-PX
CG33196-PY
CG33196-PZ
dpy-PAA
dpy-PI
dpy-PJ
dpy-PM
dpy-PO
dpy-PP
dpy-PQ
dpy-PR
dpy-PS
dpy-PT
dpy-PU
dpy-PV
dpy-PW
dpy-PX
dpy-PY
dpy-PZ
fibrillin-like
mucin related 24F

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4477462..4614300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001258947.3NP_001245876.1  dumpy, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245876.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NCR4
    Conserved Domains (8) summary
    PHA03255
    Location:79098078
    PHA03255; BDLF3; Provisional
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:1473214967
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:1487014966
    Zona_pellucida; Zona pellucida-like domain
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam15767
    Location:57566396
    DUF4696; Domain of unknown function (DUF4696)
    pfam15950
    Location:40884235
    DUF4758; Domain of unknown function (DUF4758)
  2. NM_001273110.1NP_001260039.1  dumpy, isoform X [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260039.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PCJ8
    Conserved Domains (8) summary
    PHA03255
    Location:79098078
    PHA03255; BDLF3; Provisional
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:1445214687
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:1459014686
    Zona_pellucida; Zona pellucida-like domain
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam15767
    Location:57566396
    DUF4696; Domain of unknown function (DUF4696)
    pfam15950
    Location:40884235
    DUF4758; Domain of unknown function (DUF4758)
  3. NM_001273109.1NP_001260038.1  dumpy, isoform W [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260038.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PBZ4
    Conserved Domains (7) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:1764117876
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:1777917875
    Zona_pellucida; Zona pellucida-like domain
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam15767
    Location:57566396
    DUF4696; Domain of unknown function (DUF4696)
    pfam15950
    Location:40884235
    DUF4758; Domain of unknown function (DUF4758)
  4. NM_001273108.1NP_001260037.1  dumpy, isoform V [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260037.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PB31
    Conserved Domains (10) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:2003120266
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:212247
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:2016920265
    Zona_pellucida; Zona pellucida-like domain
    pfam11235
    Location:1625016410
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam14179
    Location:1622216287
    YppG; YppG-like protein
    pfam15767
    Location:32113851
    DUF4696; Domain of unknown function (DUF4696)
    pfam15822
    Location:1648116713
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    pfam15950
    Location:15431690
    DUF4758; Domain of unknown function (DUF4758)
  5. NM_001273112.1NP_001260041.1  dumpy, isoform Z [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260041.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PEI7
    Conserved Domains (6) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:1562515860
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:1576315859
    Zona_pellucida; Zona pellucida-like domain
    pfam06247
    Location:193335
    Plasmod_Pvs28; Plasmodium ookinete surface protein Pvs28
    pfam12947
    Location:137166
    EGF_3; EGF domain
  6. NM_001273107.1NP_001260036.1  dumpy, isoform U [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260036.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PEI1
    Conserved Domains (10) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:2128421519
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:2142221518
    Zona_pellucida; Zona pellucida-like domain
    pfam11235
    Location:1750317663
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam14179
    Location:1747517540
    YppG; YppG-like protein
    pfam15767
    Location:57566396
    DUF4696; Domain of unknown function (DUF4696)
    pfam15822
    Location:1773417966
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    pfam15950
    Location:40884282
    DUF4758; Domain of unknown function (DUF4758)
  7. NM_001273106.1NP_001260035.1  dumpy, isoform T [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260035.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PC45
    Conserved Domains (10) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:2192722162
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:2206522161
    Zona_pellucida; Zona pellucida-like domain
    pfam11235
    Location:1814618306
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam14179
    Location:1811818183
    YppG; YppG-like protein
    pfam15767
    Location:57566396
    DUF4696; Domain of unknown function (DUF4696)
    pfam15822
    Location:1837718609
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    pfam15950
    Location:40884282
    DUF4758; Domain of unknown function (DUF4758)
  8. NM_001273103.1NP_001260032.1  dumpy, isoform Q [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260032.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PB30
    Conserved Domains (10) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:2257622811
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:2271422810
    Zona_pellucida; Zona pellucida-like domain
    pfam11235
    Location:1879518955
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam14179
    Location:1876718832
    YppG; YppG-like protein
    pfam15767
    Location:57566396
    DUF4696; Domain of unknown function (DUF4696)
    pfam15822
    Location:1902619258
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    pfam15950
    Location:40884282
    DUF4758; Domain of unknown function (DUF4758)
  9. NM_001273111.1NP_001260040.1  dumpy, isoform Y [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260040.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PC48
    Conserved Domains (10) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:1772217957
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:1786017956
    Zona_pellucida; Zona pellucida-like domain
    pfam06247
    Location:193335
    Plasmod_Pvs28; Plasmodium ookinete surface protein Pvs28
    pfam09310
    Location:1396614125
    PD-C2-AF1; POU domain, class 2, associating factor 1
    pfam11235
    Location:1394114101
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam14179
    Location:1391313978
    YppG; YppG-like protein
    pfam15822
    Location:1417214404
    MISS; MAPK-interacting and spindle-stabilizing protein-like
  10. NM_001273101.1NP_001260030.1  dumpy, isoform O [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260030.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PC41
    Conserved Domains (10) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:2237022605
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:2250822604
    Zona_pellucida; Zona pellucida-like domain
    pfam11235
    Location:1858918749
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam14179
    Location:1856118626
    YppG; YppG-like protein
    pfam15767
    Location:57566396
    DUF4696; Domain of unknown function (DUF4696)
    pfam15822
    Location:1882019052
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    pfam15950
    Location:40884282
    DUF4758; Domain of unknown function (DUF4758)
  11. NM_001258950.1NP_001245879.1  dumpy, isoform M [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245879.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NE82
    Conserved Domains (6) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:82068441
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:212247
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:83448440
    Zona_pellucida; Zona pellucida-like domain
    pfam06247
    Location:193335
    Plasmod_Pvs28; Plasmodium ookinete surface protein Pvs28
    pfam12947
    Location:137166
    EGF_3; EGF domain
  12. NM_001273104.1NP_001260033.1  dumpy, isoform R [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260033.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PBZ0
    Conserved Domains (10) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:2245722692
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:212247
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:2259522691
    Zona_pellucida; Zona pellucida-like domain
    pfam11235
    Location:1867618836
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam14179
    Location:1864818713
    YppG; YppG-like protein
    pfam15767
    Location:56376277
    DUF4696; Domain of unknown function (DUF4696)
    pfam15822
    Location:1890719139
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    pfam15950
    Location:39694163
    DUF4758; Domain of unknown function (DUF4758)
  13. NM_001273105.1NP_001260034.1  dumpy, isoform S [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260034.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PCJ6
    Conserved Domains (10) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:1826818503
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:1840618502
    Zona_pellucida; Zona pellucida-like domain
    pfam06247
    Location:193335
    Plasmod_Pvs28; Plasmodium ookinete surface protein Pvs28
    pfam09310
    Location:1451214671
    PD-C2-AF1; POU domain, class 2, associating factor 1
    pfam11235
    Location:1448714647
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam14179
    Location:1445914524
    YppG; YppG-like protein
    pfam15822
    Location:1471814950
    MISS; MAPK-interacting and spindle-stabilizing protein-like
  14. NM_001273113.1NP_001260042.1  dumpy, isoform AA [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260042.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PB32
    Conserved Domains (7) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:1918719422
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:1932519421
    Zona_pellucida; Zona pellucida-like domain
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam15767
    Location:57566396
    DUF4696; Domain of unknown function (DUF4696)
    pfam15950
    Location:40884282
    DUF4758; Domain of unknown function (DUF4758)
  15. NM_001258946.1NP_001245875.1  dumpy, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245875.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NER8
    Conserved Domains (8) summary
    PHA03255
    Location:79098078
    PHA03255; BDLF3; Provisional
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:1526515500
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:1540315499
    Zona_pellucida; Zona pellucida-like domain
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam15767
    Location:57566396
    DUF4696; Domain of unknown function (DUF4696)
    pfam15950
    Location:40884235
    DUF4758; Domain of unknown function (DUF4758)
  16. NM_001273102.1NP_001260031.1  dumpy, isoform P [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260031.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PEH5
    Conserved Domains (10) summary
    smart00179
    Location:255286
    EGF_CA; Calcium-binding EGF-like domain
    smart00241
    Location:2033720572
    ZP; Zona pellucida (ZP) domain
    cd00054
    Location:338373
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00100
    Location:2047520571
    Zona_pellucida; Zona pellucida-like domain
    pfam11235
    Location:1655616716
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12947
    Location:137166
    EGF_3; EGF domain
    pfam14179
    Location:1652816593
    YppG; YppG-like protein
    pfam15767
    Location:57566396
    DUF4696; Domain of unknown function (DUF4696)
    pfam15822
    Location:1678717019
    MISS; MAPK-interacting and spindle-stabilizing protein-like
    pfam15950
    Location:40884235
    DUF4758; Domain of unknown function (DUF4758)