U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Takl1 Tak1-like 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 318725, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
Takl1provided by FlyBase
Official Full Name
Tak1-like 1provided by FlyBase
Primary source
FLYBASE:FBgn0046689
Locus tag
Dmel_CG31421
See related
AllianceGenome:FB:FBgn0046689
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-AE003732.1; CG31421; Dmel\CG31421; FBgn0046689; takl1; TAKL1
Summary
Predicted to enable protein kinase activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Takl1 in Genome Data Viewer
Location:
92F13-92F13; 3-69 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20770828..20772601, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16596550..16598323, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Proteasome alpha4 subunit, Testis-specific 1 Neighboring gene uncharacterized protein Neighboring gene Syncrip Neighboring gene Fancd2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Drosophila Cancer Models Identify Functional Differences between Ret Fusions. Levinson S, et al. Cell Rep, 2016 Sep 13. PMID 27626672, Free PMC Article
  2. Association of Wolbachia with Gene Expression in Drosophila Testes. Dou W, et al. Microb Ecol, 2021 Oct. PMID 33555369
  3. A targeted UAS-RNAi screen in Drosophila larvae identifies wound closure genes regulating distinct cellular processes. Lesch C, et al. Genetics, 2010 Nov. PMID 20813879, Free PMC Article
  4. JNK signaling is needed to tolerate chromosomal instability. Wong HW, et al. Cell Cycle, 2014. PMID 24335260, Free PMC Article
  5. Some novel intron positions in conserved Drosophila genes are caused by intron sliding or tandem duplication. Lehmann J, et al. BMC Evol Biol, 2010 May 26. PMID 20500887, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables MAP kinase kinase kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables MAP kinase kinase kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in JNK cascade IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of canonical NF-kappaB signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Tak1-like 1
Names
CG31421-PA
Takl1-PA
extra2
NP_732554.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    20770828..20772601 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_169924.3 → NP_732554.1  Tak1-like 1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732554.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P83104, Q4V4Q1
    UniProtKB/TrEMBL
    Q4V4A7
    Related
    FBpp0083400
    Conserved Domains (2) summary
    smart00220
    Location:15 → 262
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14058
    Location:17 → 274
    STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P83104.1 P83104

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools