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CG31115 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 318597, updated on 4-Jan-2025

Summary

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Official Symbol
CG31115provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0051115
Locus tag
Dmel_CG31115
See related
AllianceGenome:FB:FBgn0051115
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG31115
Summary
Predicted to enable S-methyl-5-thioadenosine phosphorylase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be active in cytosol. Is expressed in spermatozoon. Human ortholog(s) of this gene implicated in biliary tract benign neoplasm and diaphyseal medullary stenosis with malignant fibrous histiocytoma. Orthologous to human MTAP (methylthioadenosine phosphorylase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG31115 in Genome Data Viewer
Location:
96B17-96B17; 3-86 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25036944..25037982)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20862666..20863704)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Hormone receptor-like in 96 Neighboring gene Smg6 Neighboring gene YTH N6-methyladenosine RNA binding protein Neighboring gene Inositol polyphosphate-5-phosphatase type I Neighboring gene baiser Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
  2. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
  3. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
  4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
  5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables S-methyl-5-thioadenosine phosphorylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables S-methyl-5-thioadenosine phosphorylase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-methionine salvage from methylthioadenosine IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nucleoside metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG31115-PB
NP_733068.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    25036944..25037982
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170189.3 → NP_733068.2  uncharacterized protein Dmel_CG31115 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733068.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8IMU4
    UniProtKB/TrEMBL
    C7LA98
    Conserved Domains (2) summary
    COG0005
    Location:12 → 266
    XapA; Purine nucleoside phosphorylase [Nucleotide transport and metabolism]
    cl00303
    Location:19 → 264
    PNP_UDP_1; Phosphorylase superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IMU4.2 Q8IMU4

Gene LinkOut

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