U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ost48 Oligosaccharyltransferase 48kD subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31849, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
Ost48provided by FlyBase
Official Full Name
Oligosaccharyltransferase 48kD subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0014868
Locus tag
Dmel_CG9022
See related
AllianceGenome:FB:FBgn0014868
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:Liang-1.11; CG9022; clone 1.11; Dmel\CG9022; DmOST50; DrOST; OST; ost48; OST48; OST48/WBP1; Ots48
Summary
Predicted to be involved in protein N-linked glycosylation via asparagine. Located in endomembrane system. Is expressed in several structures, including embryonic/larval midgut primordium; ganglia; gland; gut section; and mesoderm. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ir. Orthologous to human DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Ost48 in Genome Data Viewer
Location:
8C14-8C14; 1-26 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9156929..9158515, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9050962..9052548, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Brahma associated protein 111kD Neighboring gene Histone H3.3B Neighboring gene Dorsal interacting protein 1 Neighboring gene NADH:ubiquinone oxidoreductase subunit A3

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. PCR-mediated cloning and sequencing of the DmOST50 gene, a WBP1/AvOST50/OST48 homologue, from Drosophila melanogaster. Stagljar I, et al. Gene, 1995 Jun 9. PMID 7607543
  2. Structure and expression of histone H3.3 genes in Drosophila melanogaster and Drosophila hydei. Akhmanova AS, et al. Genome, 1995 Jun. PMID 7557364
  3. Genetic studies of mei-P26 reveal a link between the processes that control germ cell proliferation in both sexes and those that control meiotic exchange in Drosophila. Page SL, et al. Genetics, 2000 Aug. PMID 10924472, Free PMC Article
  4. Transcription in the absence of histone H3.3. Hödl M, et al. Curr Biol, 2009 Jul 28. PMID 19523831
  5. The mei-P26 gene encodes a RING finger B-box coiled-coil-NHL protein that regulates seizure susceptibility in Drosophilia. Glasscock E, et al. Genetics, 2005 Aug. PMID 15937125, Free PMC Article

See all (52) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in protein N-linked glycosylation via asparagine IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein N-linked glycosylation via asparagine IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
part_of oligosaccharyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
oligosaccharyltransferase 48kD subunit
Names
CG9022-PA
Ost48-PA
oligosaccaryltransferase 48kDa subunit

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    9156929..9158515 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078541.4 → NP_511096.2  oligosaccharyltransferase 48kD subunit [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_511096.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24319, Q24355, Q9W382
    Related
    FBpp0071279
    Conserved Domains (1) summary
    pfam03345
    Location:27 → 437
    DDOST_48kD; Oligosaccharyltransferase 48 kDa subunit beta
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q24319.2 Q24319

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous