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fend forked end [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31843, updated on 2-Nov-2024

Summary

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Official Symbol
fendprovided by FlyBase
Official Full Name
forked endprovided by FlyBase
Primary source
FLYBASE:FBgn0030090
Locus tag
Dmel_CG12664
See related
AllianceGenome:FB:FBgn0030090
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH56795; CG12664; Dmel\CG12664; Dromel_CG12664_FBtr0071349_ld14_mORF; ld14; LD14
Summary
Involved in motor neuron axon guidance. Is expressed in several structures, including abdominal lateral pentascolopidial chordotonal organ lch5; embryonic epidermis; embryonic heart cardioblast; larval central nervous system; and presumptive embryonic/larval central nervous system. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See fend in Genome Data Viewer
Location:
8C11-8C13; 1-26 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9121973..9135099, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9016006..9029132, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Adaptor Protein complex 1, gamma subunit Neighboring gene long non-coding RNA:CR45539 Neighboring gene long non-coding RNA:CR44517 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Forked end: a novel transmembrane protein involved in neuromuscular specificity in drosophila identified by gain-of-function screening. Umemiya T, et al. J Neurobiol, 2002 Jun 5. PMID 11984842
  2. Novel tools for genetic manipulation of follicle stem cells in the Drosophila ovary reveal an integrin-dependent transition from quiescence to proliferation. Hartman TR, et al. Genetics, 2015 Apr. PMID 25680813, Free PMC Article
  3. The LARK RNA-binding protein selectively regulates the circadian eclosion rhythm by controlling E74 protein expression. Huang Y, et al. PLoS One, 2007 Oct 31. PMID 17971870, Free PMC Article
  4. Genome-wide screens for in vivo Tinman binding sites identify cardiac enhancers with diverse functional architectures. Jin H, et al. PLoS Genet, 2013. PMID 23326246, Free PMC Article
  5. Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran species. Hayden CA, et al. BMC Genomics, 2008 Feb 1. PMID 18237443, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Forked end: a novel transmembrane protein involved in neuromuscular specificity in drosophila
    Title: Forked end: a novel transmembrane protein involved in neuromuscular specificity in drosophila identified by gain-of-function screening.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in motor neuron axon guidance IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
forked end
Names
CG12664-PB
CG12664-PC
fend-PB
fend-PC
ld14

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    9121973..9135099 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272443.2 → NP_001259372.1  forked end, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259372.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9GNL3, Q9W387
    UniProtKB/TrEMBL
    M9PH27

  2. NM_132300.3 → NP_572528.1  forked end, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572528.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9GNL3, Q9W387
    UniProtKB/TrEMBL
    M9PH27
    Related
    FBpp0071284
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PH27 M9PH27
Q8MS00 Q8MS00
Q9GNL3.1 Q9GNL3

Gene LinkOut

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