U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TwdlY TweedleY [ Drosophila melanogaster (fruit fly) ]

Gene ID: 318093, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
TwdlYprovided by FlyBase
Official Full Name
TweedleYprovided by FlyBase
Primary source
FLYBASE:FBgn0052570
Locus tag
Dmel_CG32570
See related
AllianceGenome:FB:FBgn0052570
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG32570; Dmel\CG32570
Summary
Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in body morphogenesis and chitin-based cuticle development. Predicted to be located in extracellular matrix. Predicted to be active in chitin-based extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See TwdlY in Genome Data Viewer
Location:
15A3-15A3; 1-55 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16734947..16735980)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16628980..16630013)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene gone early Neighboring gene TweedleX Neighboring gene TweedleZ Neighboring gene uncharacterized protein Neighboring gene Tweedlealpha

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. MOD(MDG4)-64.2 protein, isoform of MOD(MDG4) loci, directly interacts with the Tweedle protein family of Drosophila melanogaster. Golovnin AK, et al. Dokl Biochem Biophys, 2013 Sep. PMID 24150578
  2. The distribution of GYR- and YLP-like motifs in Drosophila suggests a general role in cuticle assembly and other protein-protein interactions. Cornman RS. PLoS One, 2010 Sep 2. PMID 20824096, Free PMC Article
  3. Transcriptomic Insights into the Insect Immune Response to Nematode Infection. Eleftherianos I, et al. Genes (Basel), 2021 Jan 30. PMID 33573306, Free PMC Article
  4. Annotation and analysis of low-complexity protein families of Anopheles gambiae that are associated with cuticle. Cornman RS, et al. Insect Mol Biol, 2009 Oct. PMID 19754739, Free PMC Article
  5. Molecular evolution of Drosophila cuticular protein genes. Cornman RS. PLoS One, 2009 Dec 17. PMID 20019874, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of chitin-based cuticle ISS
Inferred from Sequence or Structural Similarity
more info
  
enables structural constituent of chitin-based larval cuticle IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in body morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in chitin-based cuticle development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in chitin-based cuticle development ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in chitin-based extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular matrix ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
TweedleY
Names
CG32570-PA
TwdlY-PA
tweedle
tweedle Y

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    16734947..16735980
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_167540.4 → NP_728017.1  TweedleY [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728017.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IR10
    Related
    FBpp0074100
    Conserved Domains (1) summary
    smart00690
    Location:76 → 175
    DM5; Domain of unknown function, currently peculiar to Drosophila
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IR10 Q8IR10

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools