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CG11294 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31807, updated on 4-Jan-2025

Summary

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Official Symbol
CG11294provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030058
Locus tag
Dmel_CG11294
See related
AllianceGenome:FB:FBgn0030058
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CT31519; Dmel\CG11294
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to several human genes including ESX1 (ESX homeobox 1); RHOXF1 (Rhox homeobox family member 1); and RHOXF2 (Rhox homeobox family member 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG11294 in Genome Data Viewer
Location:
8A2-8A2; 1-24 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8691820..8693620, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8585853..8587653, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Carbonic anhydrase 3 Neighboring gene Palmitoyl-protein thioesterase 1 Neighboring gene 8-oxoguanine DNA glycosylase Neighboring gene long non-coding RNA:CR44507 Neighboring gene long non-coding RNA:CR44508 Neighboring gene Hexosaminidase 2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutations in palmitoyl-protein thioesterase 1 alter exocytosis and endocytosis at synapses in Drosophila larvae. Aby E, et al. Fly (Austin), 2013 Oct-Dec. PMID 24091420, Free PMC Article
  2. Characterization of Drosophila palmitoyl-protein thioesterase 1. Glaser RL, et al. Gene, 2003 Jul 17. PMID 12909364
  3. Pax3/7 genes reveal conservation and divergence in the arthropod segmentation hierarchy. Davis GK, et al. Dev Biol, 2005 Sep 1. PMID 16083872
  4. Joint estimates of quantitative trait locus effect and frequency using synthetic recombinant populations of Drosophila melanogaster. Macdonald SJ, et al. Genetics, 2007 Jun. PMID 17435224, Free PMC Article
  5. Evolution of homeobox genes: Q50 Paired-like genes founded the Paired class. Galliot B, et al. Dev Genes Evol, 1999 Mar. PMID 10079362

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11294-PA
CG11294-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    8691820..8693620 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272423.2 → NP_001259352.1  uncharacterized protein Dmel_CG11294, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259352.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W3C6
    Conserved Domains (1) summary
    pfam00046
    Location:29 → 80
    Homeobox; Homeobox domain

  2. NM_132272.3 → NP_572500.1  uncharacterized protein Dmel_CG11294, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572500.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W3C6
    Related
    FBpp0071169
    Conserved Domains (1) summary
    pfam00046
    Location:29 → 80
    Homeobox; Homeobox domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W3C6 Q9W3C6

Gene LinkOut

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