U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG32260 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 317943, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
CG32260provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0052260
Locus tag
Dmel_CG32260
See related
AllianceGenome:FB:FBgn0052260
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH24648; cSP232; Dmel\CG32260
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG32260 in Genome Data Viewer
Location:
64A7-64A8; 3-10 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4142364..4145966)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4142364..4145966)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ras oncogene at 64B Neighboring gene Adipokinetic hormone Neighboring gene uncharacterized protein Neighboring gene nab

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects. Cao X, et al. Insect Biochem Mol Biol, 2018 Dec. PMID 30367934, Free PMC Article
  2. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article
  3. Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. Weber AL, et al. PLoS One, 2012. PMID 22496853, Free PMC Article
  4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
  5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG32260-PA
CG32260-PC
NP_001261405.1
NP_728942.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    4142364..4145966
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274476.1 → NP_001261405.1  uncharacterized protein Dmel_CG32260, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261405.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PE97
    Conserved Domains (3) summary
    smart00020
    Location:147 → 388
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:148 → 391
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam12032
    Location:14 → 64
    CLIP; Regulatory CLIP domain of proteinases

  2. NM_168065.2 → NP_728942.1  uncharacterized protein Dmel_CG32260, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728942.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IRB8
    Related
    FBpp0073070
    Conserved Domains (3) summary
    smart00020
    Location:327 → 568
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:328 → 571
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam12032
    Location:194 → 244
    CLIP; Regulatory CLIP domain of proteinases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PE97 M9PE97
Q8IH45 Q8IH45
Q8IRB8 Q8IRB8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools