U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Spn75F Serpin 75F [ Drosophila melanogaster (fruit fly) ]

Gene ID: 317912, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Spn75Fprovided by FlyBase
Official Full Name
Serpin 75Fprovided by FlyBase
Primary source
FLYBASE:FBgn0052203
Locus tag
Dmel_CG32203
See related
AllianceGenome:FB:FBgn0052203
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
6h1; BG642378; BG642378(6h1); CG32203; Dmel\CG32203; FBgn0052203
Summary
Involved in sexual reproduction. Located in extracellular space. Is expressed in adult head. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Spn75F in Genome Data Viewer
Location:
75F9-75F9; 3-45 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19128450..19129665, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19121550..19122765, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Gemin 2 Neighboring gene uncharacterized protein Neighboring gene frizzled 2 Neighboring gene long non-coding RNA:CR45941 Neighboring gene long non-coding RNA:CR43893

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Serpins in arthropod biology. Meekins DA, et al. Semin Cell Dev Biol, 2017 Feb. PMID 27603121, Free PMC Article
  2. Predicted seminal astacin-like protease is required for processing of reproductive proteins in Drosophila melanogaster. Ravi Ram K, et al. Proc Natl Acad Sci U S A, 2006 Dec 5. PMID 17116868, Free PMC Article
  3. The Drosophila serpins: multiple functions in immunity and morphogenesis. Reichhart JM, et al. Methods Enzymol, 2011. PMID 21683256
  4. Sustained post-mating response in Drosophila melanogaster requires multiple seminal fluid proteins. Ram KR, et al. PLoS Genet, 2007 Dec. PMID 18085830, Free PMC Article
  5. Identification and analysis of serpin-family genes by homology and synteny across the 12 sequenced Drosophilid genomes. Garrett M, et al. BMC Genomics, 2009 Oct 22. PMID 19849829, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
NOT enables peptidase inhibitor activity IKR
Inferred from Key Residues
more info
 PubMed 
NOT enables serine-type endopeptidase inhibitor activity IKR
Inferred from Key Residues
more info
 PubMed 
Process Evidence Code Pubs
involved_in sexual reproduction HEP PubMed 
Component Evidence Code Pubs
located_in extracellular space HDA PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
serpin 75F
Names
BG642378
CG32203-PB
Spn75F-PB

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19128450..19129665 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001043149.2 → NP_001036614.1  serpin 75F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036614.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3DMT4, Q3HKQ3
    Conserved Domains (1) summary
    cl00137
    Location:21 → 353
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3HKQ3 Q3HKQ3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous