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CG32191 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 317903, updated on 9-Dec-2024

Summary

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Official Symbol
CG32191provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0052191
Locus tag
Dmel_CG32191
See related
AllianceGenome:FB:FBgn0052191
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5584; Dmel\CG32191
Summary
Predicted to enable sulfuric ester hydrolase activity. Human ortholog(s) of this gene implicated in mucopolysaccharidosis VI. Orthologous to human ARSB (arylsulfatase B); ARSI (arylsulfatase family member I); and ARSJ (arylsulfatase family member J). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG32191 in Genome Data Viewer
Location:
75A2-75A2; 3-45 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17806451..17809146, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17799551..17802246, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene aramis Neighboring gene uncharacterized protein Neighboring gene Cln3 Neighboring gene Ionotropic receptor 75a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. There are two distinct arylsulfatase activities in Drosophila. Pelliccia JG, et al. Biochem Genet, 1987 Aug. PMID 3447585
  2. Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Jansen IE, et al. Genome Biol, 2017 Jan 30. PMID 28137300, Free PMC Article
  3. Exploiting the Potential of Drosophila Models in Lysosomal Storage Disorders: Pathological Mechanisms and Drug Discovery. Rigon L, et al. Biomedicines, 2021 Mar 7. PMID 33800050, Free PMC Article
  4. A comprehensive study of genic variation in natural populations of Drosophila melanogaster. VI. Patterns and processes of genic divergence between D. melanogaster and its sibling species, Drosophila simulans. Choudhary M, et al. Genetics, 1992 Apr. PMID 1582561, Free PMC Article
  5. Patterns of gene expression during Drosophila mesoderm development. Furlong EE, et al. Science, 2001 Aug 31. PMID 11486054

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables sulfuric ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables sulfuric ester hydrolase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG32191-PB
CG32191-PC
NP_001287102.1
NP_730304.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    17806451..17809146 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300173.1 → NP_001287102.1  uncharacterized protein Dmel_CG32191, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287102.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C3KKB6, Q8IQS4
    Conserved Domains (3) summary
    COG3119
    Location:23 → 458
    AslA; Arylsulfatase A or related enzyme [Inorganic ion transport and metabolism]
    cd16029
    Location:27 → 408
    4-S; N-acetylgalactosamine 4-sulfatase, also called arylsulftase B
    cl20644
    Location:478 → 540
    DUF4976; Domain of unknown function (DUF4976)

  2. NM_168750.4 → NP_730304.2  uncharacterized protein Dmel_CG32191, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730304.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    C3KKB6, Q8IQS4
    Conserved Domains (3) summary
    COG3119
    Location:23 → 458
    AslA; Arylsulfatase A or related enzyme [Inorganic ion transport and metabolism]
    cd16029
    Location:27 → 408
    4-S; N-acetylgalactosamine 4-sulfatase, also called arylsulftase B
    cl20644
    Location:478 → 540
    DUF4976; Domain of unknown function (DUF4976)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IQS4 Q8IQS4

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