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Hmgb4l8 high-mobility group box 4 like 8 [ Rattus norvegicus (Norway rat) ]

Gene ID: 317584, updated on 9-Dec-2024

Summary

Official Symbol
Hmgb4l8provided by RGD
Official Full Name
high-mobility group box 4 like 8provided by RGD
Primary source
RGD:1566225
See related
EnsemblRapid:ENSRNOG00000065461 AllianceGenome:RGD:1566225
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1566225
Summary
Predicted to enable DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human HMGB4 (high mobility group box 4). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See Hmgb4l8 in Genome Data Viewer
Location:
Xq36
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (134348004..134348721)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (129470473..129471169)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (137197195..137197990)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 11 subfamily N member 2 Neighboring gene olfactory receptor family 5 subfamily BH member 3 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene serine and arginine rich splicing factor 7, pseudogene 2

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding, bending IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
high mobility group protein B4-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    134348004..134348721
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006257564.5XP_006257626.1  high mobility group protein B4-like

    See identical proteins and their annotated locations for XP_006257626.1

    UniProtKB/TrEMBL
    A0A8I6A6Y4, A0A8I6GM07
    Related
    ENSRNOP00000091560.2, ENSRNOT00000095951.2
    Conserved Domains (1) summary
    cd01390
    Location:95158
    HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...