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CG2256 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31727, updated on 4-Jan-2025

Summary

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Official Symbol
CG2256provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0029995
Locus tag
Dmel_CG2256
See related
AllianceGenome:FB:FBgn0029995
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG2256
Summary
Predicted to enable calcium ion binding activity. Predicted to be involved in regulation of signal transduction. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Orthologous to human CLXN (calaxin). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG2256 in Genome Data Viewer
Location:
7D5-7D6; 1-22 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8084018..8087213, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (7978051..7981246, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Lipid droplet subset dehydrogenase 1 Neighboring gene antisense RNA:CR45535 Neighboring gene Ubiquitin conjugating enzyme E2H Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila Swiprosin-1/EFHD2 accumulates at the prefusion complex stage during Drosophila myoblast fusion. Hornbruch-Freitag C, et al. J Cell Sci, 2011 Oct 1. PMID 21896648
  2. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
  3. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article
  4. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
  5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG2256-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    8084018..8087213 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132209.2 → NP_572437.2  uncharacterized protein Dmel_CG2256 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572437.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q1EC98, Q9W3K8
    Conserved Domains (2) summary
    cd00051
    Location:228 → 292
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:229 → 292
    EF-hand_7; EF-hand domain pair
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W3K8 Q9W3K8

Gene LinkOut

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